Biological component of cells, protein has been effectively studied and investigated using biological sensors. Photonic crystal-based sensor is highly sensitive optical nanostructure it can be manipulated to affect the motion of photon for users' application. In the proposed work microcavity based photonic crystal biosensor has been designed and investigated for its different optical sensing evaluation parameters such as transmission efficiency, sensitivity, Q factor and peak resonant wavelengths. Sensor is designed and analyzed for early detection of colon cancer tissues in blood. Radius of defect micropillar has been increased from 0.16 µm to 0.19 µm. High Quality factor 10232 has been achieved with the micro pillar radius of 0.17 µm and sensitivity 700nm/RIU. Similarly, radius of 0.16 µm, 0.18 µm and 0.19 µm has attained quality factor and sensitivity such as 5324, 7232, 8343 and 111 nm/RIU, 320 nm/RIU and 340 nm/RIU respectively. Compared other work in literature, proposed work has shown better sensing capability. Designed sensor has shown remarkable output and feasibility for future fabrication.
