Academic Journal
The neurobiology of human aggressive behavior: Neuroimaging, genetic, and neurochemical aspects. ...
| Title: | The neurobiology of human aggressive behavior: Neuroimaging, genetic, and neurochemical aspects. ... |
|---|---|
| Authors: | Cupaioli, Francesca A, Zucca, Fabio A, Caporale, Cinzia, Lesch, Klaus-Peter, Passamonti, Luca, Zecca, Luigi |
| Publisher Information: | Elsevier BV |
| Publication Year: | 2021 |
| Collection: | DataCite Metadata Store (German National Library of Science and Technology) |
| Subject Terms: | Aggression, brain regions of aggression, dopamine and serotonin in aggression, genetics of aggression, imaging of aggressive brain, Brain, Brain Chemistry, Dopamine, Gene-Environment Interaction, Humans, Neuroimaging, Serotonin |
| Description: | In modern societies, there is a strive to improve the quality of life related to risk of crimes which inevitably requires a better understanding of brain determinants and mediators of aggression. Neurobiology provides powerful tools to achieve this end. Pre-clinical and clinical studies show that changes in regional volumes, metabolism-function and connectivity within specific neural networks are related to aggression. Subregions of prefrontal cortex, insula, amygdala, basal ganglia and hippocampus play a major role within these circuits and have been consistently implicated in biology of aggression. Genetic variations in proteins regulating the synthesis, degradation, and transport of serotonin and dopamine as well as their signal transduction have been found to mediate behavioral variability observed in aggression. Gene-gene and gene-environment interactions represent additional important risk factors for aggressiveness. Considering the social burden of pathological forms of aggression, more basic and ... |
| Document Type: | article in journal/newspaper |
| Language: | English |
| DOI: | 10.17863/cam.56396 |
| Availability: | https://doi.org/10.17863/cam.56396 https://www.repository.cam.ac.uk/handle/1810/309298 |
| Rights: | open.access ; Creative Commons Attribution Non Commercial No Derivatives 4.0 International ; https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode ; cc-by-nc-nd-4.0 ; http://purl.org/coar/access_right/c_abf2 |
| Accession Number: | edsbas.C05FA0F2 |
| Database: | BASE |
| Description not available. |