Bibliographic Details
| Title: |
Lithography-free highly sensitive detection of glucose based on colloidal spheres. |
| Authors: |
DURMAZ, Habibe1 hdurmaz@kmu.edu.tr |
| Superior Title: |
Turkish Journal of Physics. 2024, Vol. 48 Issue 2, p40-49. 10p. |
| Subject Terms: |
*GLUCOSE analysis, *SURFACE plasmon resonance, *GLUCOSE oxidase, *GLUCOSE, *FINITE difference time domain method, *SPECTRAL sensitivity |
| Abstract: |
Diabetes has emerged as a global health crisis, with a substantial increase in prevalence and associated healthcare costs. The urgency for early diagnosis to prevent complications has fueled research into advanced biosensing technologies. Plasmonic sensors, leveraging localized surface plasmon resonance (LSPR), have gained prominence for their sensitivity. This study explores a metamaterial-based sensor platform comprising nanospheres fabricated through colloidal lithography. A comprehensive numerical and experimental analysis of the designed metamaterial-based sensor is presented, focusing on the spectral response at the resonance frequency of 535 nm. Finite-difference time-domain (FDTD) simulations reveal the field and charge distributions, enabling a systematic exploration of geometric parameters' impact on absorption resonance. The chosen optimum parameters are validated experimentally, demonstrating excellent agreement between numerical predictions and experimental outcomes. The spectral shifts occurring in the absorption spectrum of the sensor have demonstrated the molecular detection capability of very low concentrations of glucose oxidase, such as 0.001 ppm. Our approach, offering a cost-effective alternative to common fabrication methods, holds promise for the mass production of highly sensitive biosensors, providing a pathway for the development of advanced diagnostic tools for diabetes and other healthcare applications. [ABSTRACT FROM AUTHOR] |
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| Database: |
Academic Search Premier |