Bibliographic Details
| Title: |
Photoinduced selective perfluoroalkylation of terminal alkynes via electron donor–acceptor complexes. |
| Authors: |
Shi, Xiaolin1 (AUTHOR), Yu, Bo2 (AUTHOR), Zhou, Xin3 (AUTHOR), Yang, Yong4 (AUTHOR) yangyong@qibebt.ac.cn |
| Superior Title: |
Chemical Communications. 3/4/2024, Vol. 60 Issue 18, p2532-2535. 4p. |
| Subject Terms: |
*ELECTRON donors, *ELECTRON donor-acceptor complexes, *THYMOL, *ALKYNES, *ALKENES |
| Abstract: |
Herein, we report a photoinduced selective perfluoroalkylation of terminal alkynes driven by the noncovalent interaction between a thymol anion and fluoroalkyl iodides. By precisely tuning the reaction solvent, a wide range of 37 structurally diverse perfluoroalkylated alkynes and alkenes, including ibuprofen, empagliflozin, galactose, isoxepac and indomethacin, were obtained in up to 92% yields. Mechanistic studies reveal the formation of EDA complexes between the thymol anion and fluoroalkyl iodides. This strategy may provide an important complement to traditional approaches to prepare useful perfluoroalkylated alkynes and alkenes. [ABSTRACT FROM AUTHOR] |
|
Copyright of Chemical Communications is the property of Royal Society of Chemistry and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| Database: |
Academic Search Premier |
