Authors: de Ruijter, Jorg C.^{Aff1, IDs00217023042741_cor1}, Aisala, Heikki, Jokinen, Iina, Krogerus, Kristoffer, Rischer, Heiko, Toivari, Mervi

Superior Title: European Food Research and Technology. 249(8):1991-2000

Authors: Ylinen, Anna^{Aff1, IDs1293402201845x_cor1}, de Ruijter, Jorg C., Jouhten, Paula^{Aff1, Aff2}, Penttilä, Merja^{Aff1, Aff3}

Superior Title: Microbial Cell Factories. 21(1)

Authors: de Ruijter, Jorg C, Igarashi, Kiyohiko, Penttilä, Merja

Superior Title: FEMS Yeast Res

Subject Terms: Research Article

Relation: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204792/; http://www.ncbi.nlm.nih.gov/pubmed/32310262; http://dx.doi.org/10.1093/femsyr/foaa019

Availability: https://doi.org/10.1093/femsyr/foaa019
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204792/
http://www.ncbi.nlm.nih.gov/pubmed/32310262

Authors: de Ruijter, Jorg C., Koskela, Essi V., Nandania, Jatin, Frey, Alexander D., Velagapudi, Vidya

Contributors: Department of Bioproducts and Biosystems, Molecular biotechnology, University of Helsinki, Aalto-yliopisto, Aalto University

Subject Terms: antibody, metabolic burden, recombinant protein production, targeted metabolomics

File Description: 331-341; application/pdf

Relation: Yeast; Volume 35, issue 4; de Ruijter, J C, Koskela, E V, Nandania, J, Frey, A D & Velagapudi, V 2018, ' Understanding the metabolic burden of recombinant antibody production in Saccharomyces cerevisiae using a quantitative metabolomics approach ', Yeast, vol. 35, no. 4, pp. 331-341 . https://doi.org/10.1002/yea.3298; PURE UUID: 5f6907d8-bf3d-4e68-89a8-cf9ceab3eaff; PURE ITEMURL: https://research.aalto.fi/en/publications/5f6907d8-bf3d-4e68-89a8-cf9ceab3eaff; PURE LINK: http://www.scopus.com/inward/record.url?scp=85045135622&partnerID=8YFLogxK; PURE FILEURL: https://research.aalto.fi/files/19281979/DeRuijter_et_a_2018_Understanding_the_metabolic_Yeast.pdf; https://aaltodoc.aalto.fi/handle/123456789/30937; URN:NBN:fi:aalto-201805222377

Availability: https://doi.org/10.1002/yea.3298
https://aaltodoc.aalto.fi/handle/123456789/30937

Authors: Piirainen, Mari A., de Ruijter, Jorg C., Koskela, Essi V., Frey, Alexander D.

Superior Title: In New BIOTECHNOLOGY 25 December 2014 31(6):532-537

Authors: Piirainen, Mari A., Boer, Harry, de Ruijter, Jorg C., Frey, Alexander D.

Contributors: Department of Biotechnology and Chemical Technology, VTT Technical Research Centre of Finland, Department of Bioproducts and Biosystems, Aalto-yliopisto, Aalto University

Subject Terms: Glycoengineering, Glycosylation efficiency, MNN1, N-glycosylation, UDP-GlcNAc transporter, Yeast

File Description: application/pdf

Relation: GLYCOCONJUGATE JOURNAL; Volume 33, issue 2; Piirainen , M A , Boer , H , de Ruijter , J C & Frey , A D 2016 , ' A dual approach for improving homogeneity of a human-type N-glycan structure in Saccharomyces cerevisiae ' , Glycoconjugate Journal , vol. 33 , no. 2 , pp. 189-199 . https://doi.org/10.1007/s10719-016-9656-4; PURE UUID: 707e1861-a378-4d51-855e-40258328e9c5; PURE ITEMURL: https://research.aalto.fi/en/publications/707e1861-a378-4d51-855e-40258328e9c5; PURE LINK: http://www.scopus.com/inward/record.url?scp=84961208622&partnerID=8YFLogxK; PURE FILEURL: https://research.aalto.fi/files/9199563/Piirainen_Boer_deRuijter_Frey_revision.pdf; https://aaltodoc.aalto.fi/handle/123456789/24246; URN:NBN:fi:aalto-201701191191

Availability: https://doi.org/10.1007/s10719-016-9656-4
https://aaltodoc.aalto.fi/handle/123456789/24246

Authors: Koskela, Essi V., de Ruijter, Jorg C., Frey, Alexander D.

Contributors: Department of Bioproducts and Biosystems, Aalto-yliopisto, Aalto University

Subject Terms: Antibodies, Protein folding, Synthetic biology, Yeast

File Description: application/pdf

Relation: BIOTECHNOLOGY JOURNAL; Volume 12, issue 8; Koskela , E V , de Ruijter , J C & Frey , A D 2017 , ' Following nature's roadmap : folding factors from plasma cells led to improvements in antibody secretion in S. cerevisiae ' , BIOTECHNOLOGY JOURNAL , vol. 12 , no. 8 , 1600631 . https://doi.org/10.1002/biot.201600631; PURE UUID: 5acf6a1e-68fe-44a5-88e8-d32e7e72d9bd; PURE ITEMURL: https://research.aalto.fi/en/publications/5acf6a1e-68fe-44a5-88e8-d32e7e72d9bd; PURE LINK: http://www.scopus.com/inward/record.url?scp=85019898032&partnerID=8YFLogxK; PURE FILEURL: https://research.aalto.fi/files/32914199/CHEM_Koskela_etal_Following_nature_roadmap_2017_Biotech_journal.pdf; https://aaltodoc.aalto.fi/handle/123456789/37670; URN:NBN:fi:aalto-201905062790

Availability: https://doi.org/10.1002/biot.201600631
https://aaltodoc.aalto.fi/handle/123456789/37670

Authors: de Ruijter, Jorg C., Frey, Alexander D.

Superior Title: Applied Microbiology and Biotechnology. November 2015 99(21):9061-9071

Authors: de Ruijter, Jorg C., Koskela, Essi V., Frey, Alexander D.

Subject Terms: Research

Relation: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878073/; http://www.ncbi.nlm.nih.gov/pubmed/27216259; http://dx.doi.org/10.1186/s12934-016-0488-5

Availability: https://doi.org/10.1186/s12934-016-0488-5
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878073/
http://www.ncbi.nlm.nih.gov/pubmed/27216259

Authors: de Ruijter, Jorg C., Frey, Alexander D.

Contributors: Department of Biotechnology and Chemical Technology, Department of Bioproducts and Biosystems, Aalto-yliopisto, Aalto University

File Description: application/pdf

Relation: APPLIED MICROBIOLOGY AND BIOTECHNOLOGY; Volume 99, issue 21; de Ruijter , J C & Frey , A D 2015 , ' Analysis of antibody production in Saccharomyces cerevisiae: effects of ER protein quality control disruption ' , Applied Microbiology and Biotechnology , vol. 99 , no. 21 , pp. 9061-9071 . https://doi.org/10.1007/s00253-015-6807-7; PURE UUID: 21d48107-b051-4405-8fed-95e7e054bf9a; PURE ITEMURL: https://research.aalto.fi/en/publications/21d48107-b051-4405-8fed-95e7e054bf9a; PURE FILEURL: https://research.aalto.fi/files/9199592/De_Ruijter_and_Frey_2015.pdf; https://aaltodoc.aalto.fi/handle/123456789/23492; URN:NBN:fi:aalto-201611175569

Availability: https://doi.org/10.1007/s00253-015-6807-7
https://aaltodoc.aalto.fi/handle/123456789/23492

Authors: Piirainen, Mari A., de Ruijter, Jorg C., Koskela, Essi V., Frey, Alexander D.

Contributors: Department of Biotechnology and Chemical Technology, Department of Bioproducts and Biosystems, Aalto-yliopisto, Aalto University

File Description: application/pdf

Relation: NEW BIOTECHNOLOGY; Volume 31, issue 6; Piirainen , M A , de Ruijter , J C , Koskela , E V & Frey , A D 2014 , ' Glycoengineering of yeasts from the perspective of glycosylation efficiency ' , NEW BIOTECHNOLOGY , vol. 31 , no. 6 , pp. 532-537 . https://doi.org/10.1016/j.nbt.2014.03.001; PURE UUID: 26ebd482-4e8d-460f-8dcd-038616dce59e; PURE ITEMURL: https://research.aalto.fi/en/publications/26ebd482-4e8d-460f-8dcd-038616dce59e; PURE FILEURL: https://research.aalto.fi/files/9199773/Piirainen_etal_2014.pdf; https://aaltodoc.aalto.fi/handle/123456789/23494; URN:NBN:fi:aalto-201611175571

Availability: https://doi.org/10.1016/j.nbt.2014.03.001
https://aaltodoc.aalto.fi/handle/123456789/23494

Authors: de Ruijter, Jorg C., Jurgens, German, Frey, Alexander D.

Contributors: Nielsen, Jens

Superior Title: FEMS Yeast Research ; volume 17, issue 1, page fow104 ; ISSN 1567-1364 1567-1364

Subject Terms: Applied Microbiology and Biotechnology, General Medicine, Microbiology

Availability: https://doi.org/10.1093/femsyr/fow104
http://academic.oup.com/femsyr/article-pdf/17/1/fow104/10864161/fow104.pdf

Authors: Pylkkänen, Robert, Mohammadi, Pezhman, Arola, Suvi, de Ruijter, Jorg C., Sunagawa, Naoki, Igarashi, Kiyohiko, Penttilä, Merja

Contributors: Aalto-Yliopisto, Ministry of Education, Culture, Sports, Science and Technology, Tekes, Academy of Finland, Business Finland

Superior Title: Biomacromolecules ; volume 21, issue 10, page 4355-4364 ; ISSN 1525-7797 1526-4602

Availability: https://doi.org/10.1021/acs.biomac.0c01162

Authors: Piirainen, Mari, Boer, Harry, de Ruijter, Jorg C., Frey, Alexander D.

Superior Title: Piirainen , M , Boer , H , de Ruijter , J C & Frey , A D 2016 , ' A dual approach for improving homogeneity of a human-type N-glycan structure in Saccharomyces cerevisiae ' , Glycoconjugate Journal , vol. 33 , no. 2 , pp. 189-199 . https://doi.org/10.1007/s10719-016-9656-4

Subject Terms: Glycoengineering, Glycosylation efficiency, MNN1, N-glycosylation, UDP-GlcNAc transporter, Yeast

Availability: https://doi.org/10.1007/s10719-016-9656-4
https://cris.vtt.fi/en/publications/3c01bff9-0b88-43fb-8595-d8b9c374afdf

Authors: Pylkkänen, Robert, Mohammadi, Pezhman, Arola, Suvi, de Ruijter, Jorg C., Sunagawa, Naoki, Igarashi, Kiyohiko, Penttilä, Merja

Superior Title: Biomacromolecules; October 2020, Vol. 21 Issue: 10 p4355-4364, 10p

Authors: de Ruijter, Jorg C.¹, Jurgens, German², Frey, Alexander D.¹ alexander.frey@aalto.fi

Superior Title: FEMS Yeast Research. Jan2017, Vol. 17 Issue 1, p1-10. 10p.

Subject Terms: *YEAST genetic engineering, *IMMUNOGLOBULINS, *GENE expression, *NUCLEOTIDE sequencing, *PHENOTYPES

Authors: de Ruijter, Jorg C.

Contributors: Kemian tekniikan korkeakoulu, School of Chemical Technology, Biotekniikan ja kemian tekniikan laitos, Department of Biotechnology and Chemical Technology, Frey, Alexander D., Prof., Aalto University, Department of Biotechnology and Chemical Technology, Finland, Molecular Biotechnology, Aalto-yliopisto, Aalto University

Subject Terms: Biotechnology, Saccharomyces cerevisiae, antibody, UPR, ERAD, protein folding, cell factory

File Description: application/pdf

Relation: Aalto University publication series DOCTORAL DISSERTATIONS; 277/2016; [Publication 1]: De Ruijter J.C., Frey A.D.: Analysis of antibody production in Saccharomyces cerevisiae: effects of ER protein quality control disruption, Appl Microbiol Biotechnol 2015, 99:9061–9071, DOI:10.1007/s00253-015-6807-7; [Publication 2]: De Ruijter J.C., Koskela E.V., Frey A.D.: Enhancing antibody folding and secretion by tailoring the Saccharomyces cerevisiae endoplasmic reticulum, Microb Cell Fact 2016, 15:87, DOI:10.1186/s12934-016-0488-5; [Publication 3]: De Ruijter J.C., Jurgens G., Frey A.D.: Screening for novel genes of Saccharomyces cerevisiae involved in recombinant antibody production, FEMS Yeast Research, DOI:10.1093/femsyr/fow104; [Publication 4]: De Ruijter J.C., Koskela E.V., Nandania J., Frey A.D., Velagapudi V.: Understanding the metabolic burden of recombinant antibody production in Saccharomyces cerevisiae using a quantitative metabolomics approach, Manuscript submitted to Metabolic Engineering communications; 1799-4942 (electronic); 1799-4934 (printed); 1799-4934 (ISSN-L); https://aaltodoc.aalto.fi/handle/123456789/24109; URN:ISBN:978-952-60-7222-7

Availability: https://doi.org/10.1007/s00253-015-6807-7
https://doi.org/10.1186/s12934-016-0488-5
https://doi.org/10.1093/femsyr/fow104
https://aaltodoc.aalto.fi/handle/123456789/24109