Authors: Chaplain, Mark A. J.^Aff5, Ganesh, Mahadevan^Aff6, Graham, Ivan G.^Aff7, Lolas, Georgios^Aff5

Contributors: Sekimura, Toshio, editor^Aff1, Noji, Sumihare, editor^Aff2, Ueno, Naoto, editor^Aff3, Maini, Philip K., editor^Aff4

Superior Title: Morphogenesis and Pattern Formation in Biological Systems : Experiments and Models. :283-293

Degree: D.Sc.
Ph.D.

Authors: Rowlatt, Christopher F., Chaplain, Mark A. J., Hughes, David J., Gillespie, Stephen H., Dockrell, David H., Johannessen, Ingolfur, Bowness, Ruth

Subject Terms: SARS-CoV-2, COVID-19, individual-based model, agent-based model, within-host modelling, viral infection, infectious diseases, immune response, type I interferon, macrophages

Relation: https://zenodo.org/record/6514656; https://doi.org/10.5281/zenodo.6514656; oai:zenodo.org:6514656

Availability: https://doi.org/10.5281/zenodo.6514656
https://doi.org/10.5281/zenodo.6514655
https://zenodo.org/record/6514656

Authors: Matzavinos, Anastasios, Shtylla, Blerta, Voller, Zachary, Liu, Sijia, Chaplain, Mark A. J.

Superior Title: Bulletin of Mathematical Biology: A Journal Devoted to Research at the Junction of Computational, Theoretical and Experimental BiologyOfficial Journal of The Society for Mathematical Biology. July 2014 76(7):1590-1606

Authors: Burgess, A. E. F, Schofield, P. G., Hubbard, S. F., Chaplain, Mark A. J., Lorenzi, T.

Superior Title: Burgess , A E F , Schofield , P G , Hubbard , S F , Chaplain , M A J & Lorenzi , T 2016 , ' Dynamical patterns of coexisting strategies in a hybrid discrete-continuum spatial evolutionary game model ' , Mathematical Modelling of Natural Phenomena , vol. 11 , no. 5 , pp. 49-64 . https://doi.org/10.1051/mmnp/201611504

Subject Terms: Spatial evolutionary games, Hybrid models, Random motion, Chemotaxis, Hawk-Dove game, Spatial patterns

File Description: application/pdf

Availability: https://doi.org/10.1051/mmnp/201611504
https://risweb.st-andrews.ac.uk/portal/en/researchoutput/dynamical-patterns-of-coexisting-strategies-in-a-hybrid-discretecontinuum-spatial-evolutionary-game-model(30fd94a8-83c1-4479-ba89-19f5339e9b8c).html
https://research-repository.st-andrews.ac.uk/bitstream/10023/9625/1/Burgess_2016_Dynamical_MMNP_AAM.pdf

Authors: Boujelben, Ahmed, Watson, Michael, McDougall, Steven, Yen, Yi-Fen, Gerstner, Elizabeth, Catana, Ciprian, Deisboeck, Thomas, Batchelor, Tracy, Boas, David, Rosen, Bruce, Kalpathy-Cramer, Jayashree, Chaplain, Mark Andrew Joseph

Superior Title: Boujelben , A , Watson , M , McDougall , S , Yen , Y-F , Gerstner , E , Catana , C , Deisboeck , T , Batchelor , T , Boas , D , Rosen , B , Kalpathy-Cramer , J & Chaplain , M A J 2016 , ' Multimodality imaging and mathematical modelling of drug delivery to glioblastomas ' , Interface Focus , vol. 6 , no. 5 , 20160039 . https://doi.org/10.1098/rsfs.2016.0039

Subject Terms: Multimodality imaging, Glioblastoma, Drug delivery, Perfusion, Computational modelling and simulation

File Description: application/pdf

Availability: https://doi.org/10.1098/rsfs.2016.0039
https://risweb.st-andrews.ac.uk/portal/en/researchoutput/multimodality-imaging-and-mathematical-modelling-of-drug-delivery-to-glioblastomas(49b008ef-e16d-4cf7-a583-eff59cb85b81).html
https://research-repository.st-andrews.ac.uk/bitstream/10023/11513/1/RS_Interface_Focus_revisedpaper_july2016_finalversion.pdf

Authors: Powathil, Gibin, Munro, Alastair John, Chaplain, Mark Andrew Joseph, Swat, Maciej

Superior Title: Powathil , G , Munro , A J , Chaplain , M A J & Swat , M 2016 , ' Bystander effects and their implications for clinical radiation therapy : insights from multiscale in silico experiments ' , Journal of Theoretical Biology , vol. 401 , pp. 1-14 . https://doi.org/10.1016/j.jtbi.2016.04.010

Subject Terms: Multiscale mathematical model, Radiation therapy, Radiation-induced bystander effects, Cell-cycle

File Description: application/pdf

Availability: https://doi.org/10.1016/j.jtbi.2016.04.010
https://risweb.st-andrews.ac.uk/portal/en/researchoutput/bystander-effects-and-their-implications-for-clinical-radiation-therapy(3b1d9429-2bfb-4b29-9c00-45fe441e4532).html
https://research-repository.st-andrews.ac.uk/bitstream/10023/10615/1/JTB_Bystander_Nohighlight_R1_AAM.pdf

Authors: Chaplain, Mark Andrew Joseph, Tello, J. I.

Superior Title: Chaplain , M A J & Tello , J I 2016 , ' On the stability of homogeneous steady states of a chemotaxis system with logistic growth term ' , Applied Mathematics Letters , vol. 57 , pp. 1-6 . https://doi.org/10.1016/j.aml.2015.12.001

Subject Terms: Chemotaxis, Stability, Steady state, Lower and upper solutions

File Description: application/pdf

Availability: https://doi.org/10.1016/j.aml.2015.12.001
https://risweb.st-andrews.ac.uk/portal/en/researchoutput/on-the-stability-of-homogeneous-steady-states-of-a-chemotaxis-system-with-logistic-growth-term(91b907cb-6c10-4eab-bc55-c00798b66aec).html
https://research-repository.st-andrews.ac.uk/bitstream/10023/10087/1/Chaplain_Homogeneous_APL_AM.pdf

Authors: Macnamara, Cicely Krystyna, Chaplain, Mark Andrew Joseph

Superior Title: Macnamara , C K & Chaplain , M A J 2016 , ' Diffusion driven oscillations in gene regulatory networks ' , Journal of Theoretical Biology , vol. 407 , pp. 51-70 . https://doi.org/10.1016/j.jtbi.2016.07.021

Subject Terms: Hes1 protein, Synthetic networks, Repressilators, Activator-repressor systems, Spatial modelling

File Description: application/pdf

Availability: https://doi.org/10.1016/j.jtbi.2016.07.021
https://risweb.st-andrews.ac.uk/portal/en/researchoutput/diffusion-driven-oscillations-in-gene-regulatory-networks(160e339a-38f6-4516-90d9-b367f27fff15).html
https://research-repository.st-andrews.ac.uk/bitstream/10023/11258/1/CKMMAJC_JTB2016_author_accepted.pdf

Authors: Szymanska, Zuzanna, Morales Rodrigo, Cristian, Lachowicz, Miroslaw, Chaplain, Mark A.J.

Contributors: Universidad de Sevilla. Departamento de Ecuaciones Diferenciales y Análisis Numérico, Universidad de Sevilla. FQM131: Ec.diferenciales,Simulacion Num.y Desarrollo Software, European Union (UE)

Subject Terms: Cancer invasion of tissue, Haptotaxis, Nonlocal interactions, Existence, Uniqueness, Regularity of solutions, Computational simulations, Travelling waves

File Description: application/pdf

Relation: Mathematical Models and Methods in Applied Sciences, 19 (2), 257-281.; info:eu-repo/grantAgreement/EC/FP6/503661

Availability: https://idus.us.es/xmlui/handle/11441/45115

Authors: Domschke, Pia, Trucu, Dumitru, Gerisch, Alf, Chaplain, Mark A. J.

Subject Terms: Quantitative Biology - Cell Behavior, Quantitative Biology - Tissues and Organs, 35M30, 35Q92

Relation: http://arxiv.org/abs/1607.05353

Availability: http://arxiv.org/abs/1607.05353

Authors: Peng, Lu, Trucu, Dumitru, Lin, Ping, Thompson, Alastair, Chaplain, Mark A. J.

Subject Terms: Mathematics - Dynamical Systems, Quantitative Biology - Populations and Evolution, Quantitative Biology - Tissues and Organs

Relation: http://arxiv.org/abs/1603.07540

Availability: http://arxiv.org/abs/1603.07540

Authors: Mistry, Hitesh B., MacCallum, David E., Jackson, Robert C., Chaplain, Mark A. J., Davidson, Fordyce A.

Superior Title: Proceedings of the National Academy of Sciences of the United States of America, 2008 Dec . 105(51), 20215-20220.

Access URL: https://www.jstor.org/stable/25465805

Authors: Chaplain, Mark A. J.^Aff4, Orme, Michelle E.^Aff5

Contributors: Markwald, Roger R., editor^Aff1, Little, Charles D., editor^Aff2, Mironov, Vladimir, editor^Aff2, Sage, E. Helene, editor^Aff3

Superior Title: Vascular Morphogenesis: In Vivo, In Vitro, In Mente. :205-240

Authors: Sturrock, Marc, Hellander, Andreas, Aldakheel, Sahar, Petzold, Linda, Chaplain, Mark A. J.

Superior Title: Bulletin of Mathematical Biology: A Journal Devoted to Research at the Junction of Computational, Theoretical and Experimental BiologyOfficial Journal of The Society for Mathematical Biology. April 2014 76(4):766-798

Authors: Chaplain, Mark, Ptashnyk, Mariya, Sturrock, Marc

Contributors: University of St Andrews. Applied Mathematics

Subject Terms: Gene regulatory network, Transcription factor, Negative feedback loop, Oscillations, Hopf bifurcation, Center manifold and normal form, Weakly nonlinear analysis, QA Mathematics, QH301 Biology, NDAS, BDC, R2C, SDG 3 - Good Health and Well-being, QA, QH301

File Description: application/pdf

Relation: Mathematical Models and Methods in Applied Sciences; Chaplain , M , Ptashnyk , M & Sturrock , M 2015 , ' Hopf bifurcation in a gene regulatory network model : molecular movement causes oscillations ' , Mathematical Models and Methods in Applied Sciences , vol. 25 , no. 6 , pp. 1179-1215 . https://doi.org/10.1142/S021820251550030X; PURE: 206431985; PURE UUID: 3eb6bacf-4f3b-4c52-aff0-53fd43b75552; RIS: urn:E69CE837219A40C22A225F5D19E103EF; Scopus: 84928548767; ORCID: /0000-0001-5727-2160/work/55378988; http://hdl.handle.net/10023/7564; https://doi.org/10.1142/S021820251550030X

Availability: https://doi.org/10.1142/S021820251550030X
http://hdl.handle.net/10023/7564

Authors: Schluter, Daniela K., Ramis-Conde, Ignacio, Chaplain, Mark A. J.

Contributors: University of St Andrews. Applied Mathematics

Subject Terms: Individual-based modelling, Cell population modelling, Cell-adhesion forces, E-cadherin, QA75 Electronic computers. Computer science, RC0254 Neoplasms. Tumors. Oncology (including Cancer), NDAS, BDC, R2C, SDG 3 - Good Health and Well-being, QA75, RC0254

File Description: application/pdf

Relation: Journal of the Royal Society Interface; Schluter , D K , Ramis-Conde , I & Chaplain , M A J 2015 , ' Multi-scale modelling of the dynamics of cell colonies : insights into cell-adhesion forces and cancer invasion from in silico simulations ' , Journal of the Royal Society Interface , vol. 12 , no. 103 , 20141080 , pp. 1-13 . https://doi.org/10.1098/rsif.2014.1080; PURE: 206436327; PURE UUID: 50dc08d0-98d5-4964-9bee-c38e229b8634; RIS: urn:481794096B9C3F38BBF9E21F4DA52F11; Scopus: 85005790455; ORCID: /0000-0001-5727-2160/work/55378916; http://hdl.handle.net/10023/7571; https://doi.org/10.1098/rsif.2014.1080

Availability: https://doi.org/10.1098/rsif.2014.1080
http://hdl.handle.net/10023/7571

Authors: Kim, Yangjin, Powathil, Gibin, Kang, Hyunji, Trucu, Dumitru, Kim, Hyeongi, Lawler, Sean, Chaplain, Mark

Contributors: University of St Andrews. Applied Mathematics

Subject Terms: QA Mathematics, NDAS, SDG 3 - Good Health and Well-being, QA

File Description: application/pdf

Relation: PLoS One; Kim , Y , Powathil , G , Kang , H , Trucu , D , Kim , H , Lawler , S & Chaplain , M 2015 , ' Strategies of eradicating glioma cells : a multi-scale mathematical model with miR-451-AMPK-mTOR control ' , PLoS One , vol. 10 , no. 1 , e0114370 . https://doi.org/10.1371/journal.pone.0114370; PURE: 206440173; PURE UUID: a5276527-f288-4605-867d-f40853567686; RIS: urn:D077304928562D76A63772CFFA006762; Scopus: 84961289886; ORCID: /0000-0001-5727-2160/work/55379009; http://hdl.handle.net/10023/7503; https://doi.org/10.1371/journal.pone.0114370

Availability: https://doi.org/10.1371/journal.pone.0114370
http://hdl.handle.net/10023/7503

Authors: Hill, Lydia, Chaplain, Mark Andrew Joseph, Wolf, Roland, Kapelyukh, Yury

Superior Title: Hill , L , Chaplain , M A J , Wolf , R & Kapelyukh , Y 2015 , ' The usage of a three-compartment model to investigate the metabolic differences between hepatic reductase null and wild-type mice ' , Mathematical Medicine and Biology , vol. Advance Access . https://doi.org/10.1093/imammb/dqv029

Subject Terms: cytochrome P450 enzymes, compartment models, hepatic reductase null mice, drug metabolism

File Description: application/pdf

Availability: https://doi.org/10.1093/imammb/dqv029
https://risweb.st-andrews.ac.uk/portal/en/researchoutput/the-usage-of-a-threecompartment-model-to-investigate-the-metabolic-differences-between-hepatic-reductase-null-and-wildtype-mice(2a330f49-8a90-4a7f-8620-b8a8ed340980).html
https://research-repository.st-andrews.ac.uk/bitstream/10023/9611/1/Hill_imammb_029_AAM.pdf

Authors: Chaplain, Mark Andrew Joseph, Powathil, Gibin

Superior Title: Chaplain , M A J & Powathil , G 2015 , ' Multiscale modelling of cancer progression and treatment control : the role of intracellular heterogeneities in chemotherapy treatment ' , Biophysical Reviews and Letters , vol. 10 , no. 2 , pp. 97-114 . https://doi.org/10.1142/S1793048015500058

Subject Terms: Multiscale modelling, Cell-cycle pathway, Hypoxia, Chemotherapy

File Description: application/pdf

Availability: https://doi.org/10.1142/S1793048015500058
https://risweb.st-andrews.ac.uk/portal/en/researchoutput/multiscale-modelling-of-cancer-progression-and-treatment-control(d53a2d7e-e70b-4ebd-9a0e-14d4daa15181).html
https://research-repository.st-andrews.ac.uk/bitstream/10023/7714/1/Powathil_BRL_R3.pdf

Authors: Powathil, Gibin G., Swat, Maciej, Chaplain, Mark A. J.

Superior Title: Powathil , G G , Swat , M & Chaplain , M A J 2015 , ' Systems oncology : towards patient-specific treatment regimes informed by multiscale mathematical modelling ' , Seminars in Cancer Biology , vol. 30 , pp. 13-20 . https://doi.org/10.1016/j.semcancer.2014.02.003

Subject Terms: Hybrid multiscale model, Cell-cycle, Hypoxia, Chemotherapy, Radiation therapy

File Description: application/pdf

Availability: https://doi.org/10.1016/j.semcancer.2014.02.003
https://risweb.st-andrews.ac.uk/portal/en/researchoutput/systems-oncology(5344ef13-5dc9-4fab-ada9-2e6e37c4c144).html
https://research-repository.st-andrews.ac.uk/bitstream/10023/7713/1/Powathil_Chaplain_Maciek_SCB_Final.pdf
http://www.sciencedirect.com/science/journal/1044579X