Superior Title: Schlueter , D K , Ramis-Conde , I & Chaplain , M A J 2012 , ' Computational Modeling of Single-Cell Migration: The Leading Role of Extracellular Matrix Fibers ' , Biophysical Journal , vol. 103 , no. 6 , pp. 1141-1151 . https://doi.org/10.1016/j.bpj.2012.07.048
Subject Terms: ORIENTATION, FIBROBLASTS, ATOMIC-FORCE MICROSCOPY, INVASION, EPITHELIAL-MESENCHYMAL TRANSITION, MOVEMENT, QUANTITATIVE-ANALYSIS, SURFACES, DYNAMICS, MECHANISMS
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Superior Title: Schlueter , D K , Ramis-Conde , I & Chaplain , M A J 2012 , ' Computational Modeling of Single-Cell Migration: The Leading Role of Extracellular Matrix Fibers ' , Biophysical Journal , vol. 103 , no. 6 , pp. 1141-1151 . https://doi.org/10.1016/j.bpj.2012.07.048
Subject Terms: ORIENTATION, FIBROBLASTS, ATOMIC-FORCE MICROSCOPY, INVASION, EPITHELIAL-MESENCHYMAL TRANSITION, MOVEMENT, QUANTITATIVE-ANALYSIS, SURFACES, DYNAMICS, MECHANISMS
Availability:
https://doi.org/10.1016/j.bpj.2012.07.048
https://risweb.st-andrews.ac.uk/portal/en/researchoutput/computational-modeling-of-singlecell-migration(44b4ebc0-041b-4be1-93fa-5d76e4e9ddbb).html
Authors: Sturrock, Marc, Terry, Alan J., Xirodimas, Dimitris P., Thompson, Alastair M., Chaplain, Mark A. J.
Superior Title: Sturrock , M , Terry , A J , Xirodimas , D P , Thompson , A M & Chaplain , M A J 2011 , ' Spatio-temporal modelling of the Hes1 and p53-Mdm2 intracellular signalling pathways ' , Journal of Theoretical Biology , vol. 273 , no. 1 , pp. 15-31 . https://doi.org/10.1016/j.jtbi.2010.12.016
Subject Terms: Intracellular signalling, Negative feedback, Hes1, P53, Cancer, GENETIC-CONTROL, FEEDBACK LOOP, DNA-DAMAGE, OSCILLATORY EXPRESSION, EMBRYONIC LETHALITY, MDM2-DEFICIENT MICE, TIME DELAYS, P53 PULSES, DYNAMICS, DIFFUSION
Availability:
https://doi.org/10.1016/j.jtbi.2010.12.016
https://risweb.st-andrews.ac.uk/portal/en/researchoutput/spatiotemporal-modelling-of-the-hes1-and-p53mdm2-intracellular-signalling-pathways(8ba4e53f-a68f-4787-8325-2dac7bfefece).html
Authors: Terry, Alan J., Chaplain, Mark A. J.
Superior Title: Terry , A J & Chaplain , M A J 2011 , ' Spatio-temporal modelling of the NF-kappa B intracellular signalling pathway : the roles of diffusion, active transport, and cell geometry ' , Journal of Theoretical Biology , vol. 290 , pp. 7-26 . https://doi.org/10.1016/j.jtbi.2011.08.036
Subject Terms: NF-kappa B, Spatio-temporal model, Diffusion, Active transport, Cell geometry, p53-Mdm2 feedback loop, Gene copy-number, Oscillatory expression, Nuclear localization, Temporal control, Alpha, Dynamics, Cytoplasm, HES1, Activation
Availability:
https://doi.org/10.1016/j.jtbi.2011.08.036
https://risweb.st-andrews.ac.uk/portal/en/researchoutput/spatiotemporal-modelling-of-the-nfkappa-b-intracellular-signalling-pathway(631910e4-8dc1-44e4-9fc7-bba81c3dd7aa).html
Authors: Chaplain, Mark A. J.
Superior Title: Chaplain , M A J 2011 , ' Multiscale mathematical modelling in biology and medicine ' , IMA Journal of Applied Mathematics , vol. 76 , no. 3 , pp. 371-388 . https://doi.org/10.1093/imamat/hxr025
Subject Terms: Multiscale mathematical modelling, Cancer, Metastasis, Invasion, Cancer cell invasion, Tumor growth, In vitro, Adhesion, Dynamics, Systems, Tissue, Populations, Spheroids
Availability:
https://doi.org/10.1093/imamat/hxr025
https://risweb.st-andrews.ac.uk/portal/en/researchoutput/multiscale-mathematical-modelling-in-biology-and-medicine(22edbf2f-9ccb-4d05-a755-48381abaea29).html
Authors: Sturrock, Marc, Terry, Alan J., Xirodimas, Dimitris P., Thompson, Alastair M., Chaplain, Mark A. J.
Superior Title: Sturrock , M , Terry , A J , Xirodimas , D P , Thompson , A M & Chaplain , M A J 2011 , ' Spatio-temporal modelling of the Hes1 and p53-Mdm2 intracellular signalling pathways ' , Journal of Theoretical Biology , vol. 273 , no. 1 , pp. 15-31 . https://doi.org/10.1016/j.jtbi.2010.12.016
Subject Terms: Intracellular signalling, Negative feedback, Hes1, P53, Cancer, GENETIC-CONTROL, FEEDBACK LOOP, DNA-DAMAGE, OSCILLATORY EXPRESSION, EMBRYONIC LETHALITY, MDM2-DEFICIENT MICE, TIME DELAYS, P53 PULSES, DYNAMICS, DIFFUSION
Authors: Chaplain, Mark A. J.
Superior Title: Chaplain , M A J 2011 , ' Multiscale mathematical modelling in biology and medicine ' IMA Journal of Applied Mathematics , vol 76 , no. 3 , pp. 371-388 . DOI:10.1093/imamat/hxr025
Subject Terms: Multiscale mathematical modelling, Cancer, Metastasis, Invasion, Cancer cell invasion, Tumor growth, In vitro, Adhesion, Dynamics, Systems, Tissue, Populations, Spheroids
Availability:
https://doi.org/10.1093/imamat/hxr025
http://discovery.dundee.ac.uk/portal/en/research/multiscale-mathematical-modelling-in-biology-and-medicine(27123396-0321-4a16-bf35-a516c4c9a79e).html
http://hdl.handle.net/10588/27123396-0321-4a16-bf35-a516c4c9a79e
Authors: Terry, Alan J., Chaplain, Mark A. J.
Superior Title: Terry , A J & Chaplain , M A J 2011 , ' Spatio-temporal modelling of the NF-kappa B intracellular signalling pathway : the roles of diffusion, active transport, and cell geometry ' , Journal of Theoretical Biology , vol. 290 , pp. 7-26 . https://doi.org/10.1016/j.jtbi.2011.08.036
Subject Terms: NF-kappa B, Spatio-temporal model, Diffusion, Active transport, Cell geometry, p53-Mdm2 feedback loop, Gene copy-number, Oscillatory expression, Nuclear localization, Temporal control, Alpha, Dynamics, Cytoplasm, HES1, Activation
Authors: Enderling, Heiko, Anderson, Alexander R. A., Chaplain, Mark A. J., Beheshti, Afshin, Hlatky, Lynn, Hahnfeldt, Philip
Superior Title: Enderling , H , Anderson , A R A , Chaplain , M A J , Beheshti , A , Hlatky , L & Hahnfeldt , P 2009 , ' Paradoxical dependencies of tumor dormancy and progression on basic cell kinetics ' , Cancer Research , vol. 69 , no. 22 , pp. 8814-8821 . https://doi.org/10.1158/0008-5472.CAN-09-2115
Subject Terms: Cancer stem cells, Chronic myeloid leukaemia, Human pancreatic cancer, Prostate cancer, Spontaneous apoptosis, Automaton modeling, Colon cancer, Growth, Therapy, Dynamics
Availability:
https://doi.org/10.1158/0008-5472.CAN-09-2115
https://risweb.st-andrews.ac.uk/portal/en/researchoutput/paradoxical-dependencies-of-tumor-dormancy-and-progression-on-basic-cell-kinetics(c8aab721-4a18-4762-9e1f-bacafbe523ef).html
Authors: Joshi, Badal, Wang, Xueying, Banerjee, Sayanti, Tian, Haiyan, Matzavinos, Anastasios, Chaplain, Mark A. J.
Superior Title: Joshi , B , Wang , X , Banerjee , S , Tian , H , Matzavinos , A & Chaplain , M A J 2009 , ' On immunotherapies and cancer vaccination protocols : a mathematical modelling approach ' , Journal of Theoretical Biology , vol. 259 , no. 4 , pp. 820-827 . https://doi.org/10.1016/j.jtbi.2009.05.001
Subject Terms: Cancer vaccination, Immunotherapy, Cancer dormancy, Cancer recurrence, Cytotoxic T-lymphocytes, Immune cells competition, Bifurcation analysis, Tumor immunology, Dendritic cells, T cells, System, Growth, Dynamics, Perspectives, Vaccines
Availability:
https://doi.org/10.1016/j.jtbi.2009.05.001
https://risweb.st-andrews.ac.uk/portal/en/researchoutput/on-immunotherapies-and-cancer-vaccination-protocols(c6d6a49c-4cd3-4954-8f1c-8ac7ff6bfcf1).html
Authors: Enderling, Heiko, Anderson, Alexander R. A., Chaplain, Mark A. J., Beheshti, Afshin, Hlatky, Lynn, Hahnfeldt, Philip
Superior Title: Enderling , H , Anderson , A R A , Chaplain , M A J , Beheshti , A , Hlatky , L & Hahnfeldt , P 2009 , ' Paradoxical dependencies of tumor dormancy and progression on basic cell kinetics ' , Cancer Research , vol. 69 , no. 22 , pp. 8814-8821 . https://doi.org/10.1158/0008-5472.CAN-09-2115
Subject Terms: Cancer stem cells, Chronic myeloid leukaemia, Human pancreatic cancer, Prostate cancer, Spontaneous apoptosis, Automaton modeling, Colon cancer, Growth, Therapy, Dynamics
Authors: Joshi, Badal, Wang, Xueying, Banerjee, Sayanti, Tian, Haiyan, Matzavinos, Anastasios, Chaplain, Mark A. J.
Superior Title: Joshi , B , Wang , X , Banerjee , S , Tian , H , Matzavinos , A & Chaplain , M A J 2009 , ' On immunotherapies and cancer vaccination protocols : a mathematical modelling approach ' , Journal of Theoretical Biology , vol. 259 , no. 4 , pp. 820-827 . https://doi.org/10.1016/j.jtbi.2009.05.001
Subject Terms: Cancer vaccination, Immunotherapy, Cancer dormancy, Cancer recurrence, Cytotoxic T-lymphocytes, Immune cells competition, Bifurcation analysis, Tumor immunology, Dendritic cells, T cells, System, Growth, Dynamics, Perspectives, Vaccines
Superior Title: Ramis-Conde , I , Drasdo , D , Anderson , A R A & Chaplain , M A J 2008 , ' Modeling the Influence of the E-Cadherin-?-Catenin Pathway in Cancer Cell Invasion : a multiscale approach ' , Biophysical Journal , vol. 95 , no. 1 , pp. 155-165 . https://doi.org/10.1529/biophysj.107.114678
Subject Terms: Tumor growth, In vitro, Adhesion, Micropheology, Progression, Expression, Mechanism, Dynamics, Systems
Availability:
https://doi.org/10.1529/biophysj.107.114678
https://risweb.st-andrews.ac.uk/portal/en/researchoutput/modeling-the-influence-of-the-ecadherincatenin-pathway-in-cancer-cell-invasion(594c0eb1-6133-4074-bb46-84185899e8ba).html
Superior Title: Ramis-Conde , I , Drasdo , D , Anderson , A R A & Chaplain , M A J 2008 , ' Modeling the Influence of the E-Cadherin-β-Catenin Pathway in Cancer Cell Invasion : a multiscale approach ' , Biophysical Journal , vol. 95 , no. 1 , pp. 155-165 . https://doi.org/10.1529/biophysj.107.114678
Subject Terms: Tumor growth, In vitro, Adhesion, Micropheology, Progression, Expression, Mechanism, Dynamics, Systems