Authors: Forsberg, Zarah, Stepnov, Anton A., Tesei, Giulio, Wang, Yong, Buchinger, Edith, Kristiansen, Sandra K., Aachmann, Finn L., Arleth, Lise, Eijsink, Vincent G.H., Lindorff-Larsen, Kresten, Courtade, Gaston

Superior Title: Forsberg , Z , Stepnov , A A , Tesei , G , Wang , Y , Buchinger , E , Kristiansen , S K , Aachmann , F L , Arleth , L , Eijsink , V G H , Lindorff-Larsen , K & Courtade , G 2023 , ' The effect of linker conformation on performance and stability of a two-domain lytic polysaccharide monooxygenase ' , Journal of Biological Chemistry , vol. 299 , no. 11 , 105262 . https://doi.org/10.1016/j.jbc.2023.105262

Subject Terms: carbohydrate-active enzyme, flexible linkers, lytic polysaccharide monooxygenase (LPMO), molecular dynamics, multidomain, NMR, SAXS

File Description: application/pdf

Availability: https://doi.org/10.1016/j.jbc.2023.105262
https://curis.ku.dk/portal/da/publications/the-effect-of-linker-conformation-on-performance-and-stability-of-a-twodomain-lytic-polysaccharide-monooxygenase(c33f4dc4-f222-45da-85a0-79a4d20c0532).html
https://curis.ku.dk/ws/files/371923702/1_s2.0_S0021925823022901_main.pdf

Authors: Sun, Peicheng, Huang, Zhiyu, Banerjee, Sanchari, Kadowaki, Marco A. S., Veersma, Romy J., Magri, Silvia, Hilgers, Roelant, Muderspach, Sebastian J., Laurent, Christophe V. F. P., Ludwig, Roland, Cannella, David, Lo Leggio, Leila, van Berkel, Willem J. H., Kabel, Mirjam A.

Superior Title: Sun , P , Huang , Z , Banerjee , S , Kadowaki , M A S , Veersma , R J , Magri , S , Hilgers , R , Muderspach , S J , Laurent , C V F P , Ludwig , R , Cannella , D , Lo Leggio , L , van Berkel , W J H & Kabel , M A 2023 , ' AA16 Oxidoreductases Boost Cellulose-Active AA9 Lytic Polysaccharide Monooxygenases from Myceliophthora thermophila ' , ACS Catalysis , vol. 13 , no. 7 , pp. 4454-4467 . https://doi.org/10.1021/acscatal.3c00874

Subject Terms: cellulose, Carbohydrate-Active enZyme, copper-dependent oxidoreductase, fungal auxiliary activity family, hydrogen peroxide, lytic polysaccharide monooxygenase, protein structure, CELLOBIOSE DEHYDROGENASE, OXIDATIVE CLEAVAGE, WEB SERVER, ENZYMES, DEGRADATION, BIOMASS, DISCOVERY, OXIDASE, DALI

File Description: application/pdf

Availability: https://doi.org/10.1021/acscatal.3c00874
https://curis.ku.dk/portal/da/publications/aa16-oxidoreductases-boost-celluloseactive-aa9-lytic-polysaccharide-monooxygenases-from-myceliophthora-thermophila(b31af04b-ebfb-4708-8721-fca79f49ca47).html
https://curis.ku.dk/ws/files/342607915/acscatal.3c00874.pdf

Authors: Mellor, Silas B., Behrendorff, James B. Y. H., Ipsen, Johan O., Crocoll, Christoph, Laursen, Tomas, Gillam, Elizabeth M. J., Pribil, Mathias

Superior Title: Mellor , S B , Behrendorff , J B Y H , Ipsen , J O , Crocoll , C , Laursen , T , Gillam , E M J & Pribil , M 2023 , ' Exploiting photosynthesis-driven P450 activity to produce indican in tobacco chloroplasts ' , Frontiers in Plant Science , vol. 13 , 1049177 . https://doi.org/10.3389/fpls.2022.1049177

Subject Terms: cytochrome P450, chloroplast, indigo, transient expression, photosynthesis, ferredoxin, metabolic engineering, FLAVIN-CONTAINING MONOOXYGENASE, PLANT, CYTOCHROME-P450, FLAVODOXIN, EXPRESSION, BIOSYNTHESIS, ENZYMES, DISCOVERY

File Description: application/pdf

Availability: https://doi.org/10.3389/fpls.2022.1049177
https://curis.ku.dk/portal/da/publications/exploiting-photosynthesisdriven-p450-activity-to-produce-indican-in-tobacco-chloroplasts(dc591be5-0ead-44e4-8459-c90535e88790).html
https://curis.ku.dk/ws/files/337593289/fpls_13_1049177.pdf

Authors: Tandrup, Tobias, Lo Leggio, Leila, Meilleur, Flora

Superior Title: Tandrup , T , Lo Leggio , L & Meilleur , F 2023 , ' Joint X-ray/neutron structure of Lentinus similis AA9_A at room temperature ' , Acta crystallographica. Section F, Structural biology communications , vol. 79 , no. 1 , pp. 1-7 . https://doi.org/10.1107/S2053230X22011335

Subject Terms: copper metalloenzymes, Lentinus similis AA9_A, lytic polysaccharide monooxygenases, neutron crystallography, protonation states

File Description: application/pdf

Availability: https://doi.org/10.1107/S2053230X22011335
https://curis.ku.dk/portal/da/publications/joint-xrayneutron-structure-of-lentinus-similis-aa9a-at-room-temperature(cbc50852-e9b2-4de1-af71-4d96b6c75fbe).html
https://curis.ku.dk/ws/files/335422972/or5031.pdf

Authors: Phuong Tuyen Nguyen, Wacker, Theresa, Brown, Alistair J. P., Dantas, Alessandra da Silva, Shekhova, Elena

Superior Title: Phuong Tuyen Nguyen , Wacker , T , Brown , A J P , Dantas , A D S & Shekhova , E 2022 , ' Understanding the Role of Nitronate Monooxygenases in Virulence of the Human Fungal Pathogen Aspergillus fumigatus ' , Journal of Fungi , vol. 8 , no. 7 , 736 . https://doi.org/10.3390/jof8070736

Subject Terms: redox biology, Aspergillus fumigatus, macrophages, peroxynitrite, nitronate monooxygenases, NITRIC-OXIDE, CELL, SYSTEM, RESISTANCE, INFECTION, DATABASE, DEFENSE, HEALTH

File Description: application/pdf

Availability: https://doi.org/10.3390/jof8070736
https://curis.ku.dk/portal/da/publications/understanding-the-role-of-nitronate-monooxygenases-in-virulence-of-the-human-fungal-pathogen-aspergillus-fumigatus(ccdcfe59-6d70-4935-9d26-9105317897cf).html
https://curis.ku.dk/ws/files/318428323/jof_08_00736.pdf

Authors: Banerjee, Sanchari, Muderspach, Sebastian J., Tandrup, Tobias, Frandsen, Kristian Erik Høpfner, Singh, Raushan K., Ipsen, Johan Orskov, Hernandez-Rollan, Cristina, Nørholm, Morten H. H., Bjerrum, Morten J., Johansen, Katja Salomon, Lo Leggio, Leila

Superior Title: Banerjee , S , Muderspach , S J , Tandrup , T , Frandsen , K E H , Singh , R K , Ipsen , J O , Hernandez-Rollan , C , Nørholm , M H H , Bjerrum , M J , Johansen , K S & Lo Leggio , L 2022 , ' Protonation State of an Important Histidine from High Resolution Structures of Lytic Polysaccharide Monooxygenases ' , Biomolecules , vol. 12 , no. 2 , 194 . https://doi.org/10.3390/biom12020194

Subject Terms: polysaccharide monooxygenase, protonation, stereochemical properties, partial unrestrained refinement, auxiliary activities, SECONDARY COORDINATION SPHERE, GLYCOSIDE HYDROLASE, OXYGEN ACTIVATION, PK(A) VALUES, ACTIVE-SITE, ENZYMES, MECHANISMS, CELLULOSE, PROTEINS, CLEAVAGE

File Description: application/pdf

Availability: https://doi.org/10.3390/biom12020194
https://curis.ku.dk/portal/da/publications/protonation-state-of-an-important-histidine-from-high-resolution-structures-of-lytic-polysaccharide-monooxygenases(cc81fdd8-f6d6-4629-8c9a-c6ebeb940753).html
https://curis.ku.dk/ws/files/301704280/biomolecules_12_00194_v2.pdf

Authors: Hallas-Moller, Magnus, Johansen, Katja S.

Superior Title: Hallas-Moller , M & Johansen , K S 2022 , ' Allorecognition : Knowing friend from foe ' , eLife , vol. 11 , e83121 . https://doi.org/10.7554/eLife.83121

Subject Terms: allorecognition, polysaccharide monooxygenase, somatic cell fusion, non self recognition, cell fusion checkpoint, chitin, Neurospora

File Description: application/pdf

Availability: https://doi.org/10.7554/eLife.83121
https://curis.ku.dk/portal/da/publications/allorecognition(a2c2a879-76f9-4be1-a5f1-143baf18d8b2).html
https://curis.ku.dk/ws/files/328550482/Knowing_friend_from_foe.pdf

Authors: Tokin, Radina, Frandsen, Kristian E. H., Ipsen, Johan Ørskov, Lo Leggio, Leila, Poojary, Mahesha M., Berrin, Jean-Guy, Grisel, Sacha, Brander, Søren, Jensen, Poul Erik, Johansen, Katja Salomon

Superior Title: Tokin , R , Frandsen , K E H , Ipsen , J Ø , Lo Leggio , L , Poojary , M M , Berrin , J-G , Grisel , S , Brander , S , Jensen , P E & Johansen , K S 2021 , ' Inhibition of lytic polysaccharide monooxygenase by natural plant extracts ' , New Phytologist , vol. 232 , no. 3 , pp. 1337–1349 . https://doi.org/10.1111/nph.17676

Subject Terms: Cinnamomum cassia, cinnamtannin B1, inhibitor, Lentinus similis, LPMO, lytic polysaccharide monooxygenase, plant extract

File Description: application/pdf

Availability: https://doi.org/10.1111/nph.17676
https://curis.ku.dk/portal/da/publications/inhibition-of-lytic-polysaccharide-monooxygenase-by-natural-plant-extracts(6bfa1079-33b8-40cf-ad66-d04de128fc10).html
https://curis.ku.dk/ws/files/276232304/Inhibition_of_lytic_polysaccharide_monooxygenase_by_natural_plant_extracts_accepted_version_.pdf

Authors: Brander, Søren, Lausten, Stine, Ipsen, Johan, Falkenberg, Kristoffer B., Bertelsen, Andreas B., Nørholm, Morten H.H., Østergaard, Lars H., Johansen, Katja S.

Superior Title: Brander , S , Lausten , S , Ipsen , J , Falkenberg , K B , Bertelsen , A B , Nørholm , M H H , Østergaard , L H & Johansen , K S 2021 , ' Colorimetric LPMO assay with direct implication for cellulolytic activity ' , Biotechnology for Biofuels , vol. 14 , no. 1 , 51 . https://doi.org/10.1186/s13068-021-01902-4

Subject Terms: Cellulose, Dehydroascorbate, Enzyme assay, High throughput, Lytic polysaccharide monooxygenase, Phenolphthalein

File Description: application/pdf

Availability: https://doi.org/10.1186/s13068-021-01902-4
https://curis.ku.dk/portal/da/publications/colorimetric-lpmo-assay-with-direct-implication-for-cellulolytic-activity(8cf6d153-acc2-4b9d-b2b1-2cd0febcb2bb).html
https://curis.ku.dk/ws/files/259678010/s13068_021_01902_4.pdf

Authors: Dodge, N., Russo, D. A., Blossom, B. M., Singh, R. K., van Oort, B., Croce, R., Bjerrum, M. J., Jensen, P. E.

Superior Title: Dodge , N , Russo , D A , Blossom , B M , Singh , R K , van Oort , B , Croce , R , Bjerrum , M J & Jensen , P E 2020 , ' Water-soluble chlorophyll-binding proteins from Brassica oleracea allow for stable photobiocatalytic oxidation of cellulose by a lytic polysaccharide monooxygenase ' , Biotechnology for Biofuels , vol. 13 , 192 . https://doi.org/10.1186/s13068-020-01832-7

Subject Terms: Cellulose, Chlorophyll-binding protein, Light-driven, Monooxygenases, Photobiocatalysis

File Description: application/pdf

Availability: https://doi.org/10.1186/s13068-020-01832-7
https://curis.ku.dk/portal/da/publications/watersoluble-chlorophyllbinding-proteins-from-brassica-oleracea-allow-for-stable-photobiocatalytic-oxidation-of-cellulose-by-a-lytic-polysaccharide-monooxygenase(a7fe1345-0b97-44a5-a6a8-a0f13c743c32).html
https://curis.ku.dk/ws/files/254660563/Water_soluble_chlorophyll_binding_proteins_from_Brassica_oleracea_allow_for_stable_photobiocatalytic_oxidation_of_cellulose_by_a_lytic_polysaccharide_monooxygenase.pdf

Authors: Blossom, Benedikt M., Russo, David A., Singh, Raushan K., Van Oort, Bart, Keller, Malene B., Simonsen, Tor, Perzon, Alixander, Gamon, Luke F., Davies, Michael J., Cannella, David, Croce, Roberta, Jensen, Poul Erik, Bjerrum, Morten J., Felby, Claus

Superior Title: Blossom , B M , Russo , D A , Singh , R K , Van Oort , B , Keller , M B , Simonsen , T , Perzon , A , Gamon , L F , Davies , M J , Cannella , D , Croce , R , Jensen , P E , Bjerrum , M J & Felby , C 2020 , ' Photobiocatalysis by a Lytic Polysaccharide Monooxygenase Using Intermittent Illumination ' , ACS Sustainable Chemistry & Engineering , vol. 8 , no. 25 , pp. 9301-9310 . https://doi.org/10.1021/acssuschemeng.0c00702

Subject Terms: Photobiocatalysis, Lytic polysaccharide monooxygenases, Cellulose oxidation, Intermittent light, Reactive oxygen species (ROS), Photosensitizer, Chlorophyllin, CELLULOSE, COPPER, DEGRADATION, OXIDATION, ENZYMES

File Description: application/pdf

Availability: https://doi.org/10.1021/acssuschemeng.0c00702
https://curis.ku.dk/portal/da/publications/photobiocatalysis-by-a-lytic-polysaccharide-monooxygenase-using-intermittent-illumination(64b46740-5bcd-408b-8ea2-27421016c375).html
https://curis.ku.dk/ws/files/244994960/Photobiocatalysis_by_a_Lytic_Polysaccharide_Monooxygenase_Using_Intermittent_Illumination.pdf

Authors: Goetze, Jens P., Voiosu, Andrei, Wiese, Signe, Schulte, Janin, Kaufmann, Paul, Bergmann, Andreas, Bartels, Emil D., Møller, Søren

Superior Title: Goetze , J P , Voiosu , A , Wiese , S , Schulte , J , Kaufmann , P , Bergmann , A , Bartels , E D & Møller , S 2023 , ' Peptidylglycine α-amidating monooxygenase and adrenomedullin measurement in patients with hepatic cirrhosis ' , Biomarkers in Medicine , vol. 17 , no. 13 , pp. 577-583 . https://doi.org/10.2217/bmm-2023-0337

Subject Terms: ADM, bioactive adrenomedullin, cirrhosis, heart failure, PAM, peptidylglycine α-amidating monooxygenase, proadrenomedullin

Availability: https://doi.org/10.2217/bmm-2023-0337
https://curis.ku.dk/portal/da/publications/peptidylglycine-amidating-monooxygenase-and-adrenomedullin-measurement-in-patients-with-hepatic-cirrhosis(0f147f4c-cb8e-4f53-ab06-5d51006b7a97).html

Authors: Cannella, David, Weiss, Noha, Hsieh, Carmen, Magri, Silvia, Zarattini, Marco, Kuska, Justyna, Karuna, Nardrapee, Thygesen, Lisbeth G., Polikarpov, Igor, Felby, Claus, Jeoh, Tina, Jørgensen, Henning

Superior Title: Cannella , D , Weiss , N , Hsieh , C , Magri , S , Zarattini , M , Kuska , J , Karuna , N , Thygesen , L G , Polikarpov , I , Felby , C , Jeoh , T & Jørgensen , H 2023 , ' LPMO-mediated oxidation increases cellulose wettability, surface water retention and hydrolysis yield at high dry matter ' , Cellulose , vol. 30 , pp. 6259–6272 . https://doi.org/10.1007/s10570-023-05271-z

Subject Terms: Cellulose hydrolysis, Cellulose oxidation, Cellulose wettability, High dry matter, Lytic polysaccharide monooxygenase, Water retation

Availability: https://doi.org/10.1007/s10570-023-05271-z
https://curis.ku.dk/portal/da/publications/lpmomediated-oxidation-increases-cellulose-wettability-surface-water-retention-and-hydrolysis-yield-at-high-dry-matter(d6a49045-4aad-4df6-b6eb-88e43f5915aa).html

Authors: Frandsen, Kristian Erik Høpfner, Poulsen, Jens-Christian Navarro, Tovborg, Morten, Johansen, Katja Salomon, Lo Leggio, Leila

Superior Title: Frandsen , K E H , Poulsen , J-C N , Tovborg , M , Johansen , K S & Lo Leggio , L 2017 , ' Learning from oligosaccharide soaks of crystals of an AA13 lytic polysaccharide monooxygenase : crystal packing, ligand binding and active-site disorder ' , Acta crystallographica Section D: Structural biology , vol. 73 , pp. 64-76 . https://doi.org/10.1107/S2059798316019641

Subject Terms: lytic polysaccharide monooxygenases, LPMOs, starch degradation, active-site stability, biomass utilization

File Description: application/pdf

Availability: https://doi.org/10.1107/S2059798316019641
https://curis.ku.dk/portal/da/publications/learning-from-oligosaccharide-soaks-of-crystals-of-an-aa13-lytic-polysaccharide-monooxygenase(607a83e1-c5df-448b-b8be-8d550dd6b394).html
https://curis.ku.dk/ws/files/173904546/dw5173_reprint.pdf

Authors: Frandsen, Kristian Erik Høpfner, Lo Leggio, Leila

Superior Title: Frandsen , K E H & Lo Leggio , L 2016 , ' Lytic polysaccharide monooxygenases : a crystallographer's view on a new class of biomass-degrading enzymes ' , IUCrJ , vol. 3 , no. Part 6 , pp. 448-467 . https://doi.org/10.1107/S2052252516014147

Subject Terms: lytic polysaccharide monooxygenases, carbohydrate-modifying enzymes, metalloproteins, copper enzymes, biomass degradation

File Description: application/pdf

Availability: https://doi.org/10.1107/S2052252516014147
https://curis.ku.dk/portal/da/publications/lytic-polysaccharide-monooxygenases(7ce2e30b-b02a-4197-96d5-6a90bac3470e).html
https://curis.ku.dk/ws/files/169640848/Frandsen_2016_Lytic_polysaccharide.pdf

Authors: Brander, Søren, Tokin, Radina, Ipsen, Johan, Jensen, Poul Erik, Hernández-Rollán, Cristina, Nørholm, Morten H.H., Lo Leggio, Leila, Dupree, Paul, Johansen, Katja S.

Superior Title: Brander , S , Tokin , R , Ipsen , J , Jensen , P E , Hernández-Rollán , C , Nørholm , M H H , Lo Leggio , L , Dupree , P & Johansen , K S 2021 , ' Scission of Glucosidic Bonds by a Lentinus similis Lytic Polysaccharide Monooxygenases Is Strictly Dependent on H 2 O 2 while the Oxidation of Saccharide Products Depends on O 2 ' , ACS Catalysis , vol. 11 , no. 22 , pp. 13848-13859 . https://doi.org/10.1021/acscatal.1c04248

Subject Terms: cellulose, hydrolysis, lytic polysaccharide monooxygenase, mononuclear copper enzyme, saccharide radical

Availability: https://doi.org/10.1021/acscatal.1c04248
https://curis.ku.dk/portal/da/publications/scission-of-glucosidic-bonds-by-a-lentinus-similis-lytic-polysaccharide-monooxygenases-is-strictly-dependent-on-h2o2while-the-oxidation-of-saccharide-products-depends-on-o2(e8603dbb-e731-4460-9d6c-2f4814e9e64b).html

Authors: Cedergreen, Nina, Bellisai, Giulia, Herrero-Nogareda, Laia, Boesen, Emil, Dalhoff, Kristoffer

Superior Title: Cedergreen , N , Bellisai , G , Herrero-Nogareda , L , Boesen , E & Dalhoff , K 2021 , ' Using TKTD Models in Combination with In Vivo Enzyme Inhibition Assays to Investigate the Mechanisms behind Synergistic Interactions across Two Species ' , Environmental Science & Technology , vol. 55 , no. 20 , pp. 13990-13999 . https://doi.org/10.1021/acs.est.1c02222

Subject Terms: Chironomus riparius, Daphnia magna, mixture toxicity, P450 monooxygenase activity, chemical interactions, species extrapolation

Availability: https://doi.org/10.1021/acs.est.1c02222
https://curis.ku.dk/portal/da/publications/using-tktd-models-in-combination-with-in-vivo-enzyme-inhibition-assays-to-investigate-the-mechanisms-behind-synergistic-interactions-across-two-species(99ea6a35-de9c-495f-9a33-d50065a9be5f).html

Authors: Higasi, Paula M. R., Velasco, Josman A., Pellegrini, Vanessa O. A., de Araujo, Evandro A., Franca, Bruno Alves, Keller, Malene B., Labate, Carlos A., Blossom, Benedikt M., Segato, Fernando, Polikarpov, Igor

Superior Title: Higasi , P M R , Velasco , J A , Pellegrini , V O A , de Araujo , E A , Franca , B A , Keller , M B , Labate , C A , Blossom , B M , Segato , F & Polikarpov , I 2021 , ' Light-stimulated T. thermophilus two-domain LPMO9H : Low-resolution SAXS model and synergy with cellulases ' , Carbohydrate Polymers , vol. 260 , 117814 . https://doi.org/10.1016/j.carbpol.2021.117814

Subject Terms: Cellulose, Lytic polysaccharide monooxygenase, CAZymes

Availability: https://doi.org/10.1016/j.carbpol.2021.117814
https://curis.ku.dk/portal/da/publications/lightstimulated-t-thermophilus-twodomain-lpmo9h(78c6a195-fb75-4d03-b723-3d287851a7a5).html

Authors: Lau, Ian C.K., Feyereisen, René, Nelson, David R., Bell, Stephen G.

Superior Title: Lau , I C K , Feyereisen , R , Nelson , D R & Bell , S G 2019 , ' Analysis and preliminary characterisation of the cytochrome P450 monooxygenases from Frankia sp. EuI1c ( Frankia inefficax sp.) ' , Archives of Biochemistry and Biophysics , vol. 669 , pp. 11-21 . https://doi.org/10.1016/j.abb.2019.05.007

Subject Terms: Bacterial metabolism, Cytochrome P450 monooxygenases, Ferredoxins, Frankia, Terpenoids

Availability: https://doi.org/10.1016/j.abb.2019.05.007
https://curis.ku.dk/portal/da/publications/analysis-and-preliminary-characterisation-of-the-cytochrome-p450-monooxygenases-from-frankia-sp-eui1c-frankia-inefficax-sp(f7d09ee5-af28-4272-9577-853c1fbb6b42).html
http://www.scopus.com/inward/record.url?scp=85065891866&partnerID=8YFLogxK

Authors: Gold, Nicholas D., Fossati, Elena, Hansen, Cecilie Ida Cetti, DiFalco, Marcos, Douchin, Veronique, Martin, Vincent J.J.

Superior Title: Gold , N D , Fossati , E , Hansen , C I C , DiFalco , M , Douchin , V & Martin , V J J 2018 , ' A Combinatorial Approach To Study Cytochrome P450 Enzymes for De Novo Production of Steviol Glucosides in Baker’s Yeast ' , A C S Synthetic Biology , vol. 7 , no. 12 , pp. 2918-2929 . https://doi.org/10.1021/acssynbio.8b00470

Subject Terms: cytochrome P450 monooxygenase, cytochrome P450 reductase, diterpenoid biosynthesis, steviol glucosides

Availability: https://doi.org/10.1021/acssynbio.8b00470
https://curis.ku.dk/portal/da/publications/a-combinatorial-approach-to-study-cytochrome-p450-enzymes-for-de-novo-production-of-steviol-glucosides-in-bakers-yeast(16d45d67-35b7-4a97-8553-b45b48385d36).html