Authors: Nowrouzi, B, Lungang, L, Rios-Solis, L

Superior Title: Microbial Cell Factories , 21 , Article 197. (2022)

Subject Terms: Taxol®, CYP725A4, Cytochrome P450 monooxygenase, Taxadiene-5α-ol, Saccharomyces cerevisiae, Diterpenoids, Whole-cell biocatalysis

File Description: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10183103/1/Rios-Solis_Exploring%20optimal%20Taxol%20CYP725A4%20activity%20in%20Saccharomyces%20cerevisiae%20%20%20%20.pdf; https://discovery.ucl.ac.uk/id/eprint/10183103/

Availability: https://discovery.ucl.ac.uk/id/eprint/10183103/1/Rios-Solis_Exploring%20optimal%20Taxol%20CYP725A4%20activity%20in%20Saccharomyces%20cerevisiae%20%20%20%20.pdf
https://discovery.ucl.ac.uk/id/eprint/10183103/

Authors: Wild, EJ, Tabrizi, SJ

Superior Title: Movement Disorders , 29 (11) pp. 1434-1445. (2014)

Subject Terms: HDAC inhibition, Huntington's disease, MAPK, gene silencing, glial cells, kynurenine monooxygenase, phosphodiesterase inhibition, therapeutics

File Description: application/pdf

Availability: http://discovery.ucl.ac.uk/1443932/2/mds26007.pdf
http://discovery.ucl.ac.uk/1443932/

Authors: Veeramah, KR, Thomas, MG, Weale, ME, Zeitlyn, D, Tarekegn, A, Bekele, E, Mendell, NR, Shephard, EA, Bradman, N, Phillips, IR

Superior Title: PHARMACOGENET GENOM , 18 (10) 877 - 886. (2008)

Subject Terms: drug metabolism, flavin-containing monooxygenase, flavin-containing monooxygenase 2, long-range haplotype test, pharmacogenetics, sub-Saharan Africa, RECENT POSITIVE SELECTION, MYCOBACTERIUM-TUBERCULOSIS, EXPRESSED PROTEIN, DRUG-METABOLISM, S-OXYGENATION, GENE FAMILY, HUMAN LUNG, FMO2, IDENTIFICATION, POLYMORPHISMS

Availability: http://discovery.ucl.ac.uk/150148/

Authors: Fennema, D, Phillips, IR, Shephard, EA

Superior Title: Drug Metabolism and Disposition (2016) (In press).

Subject Terms: flavin-containing monooxygenase/FMO, microbiome

Availability: http://discovery.ucl.ac.uk/1494862/

Authors: Shephard, EA, Treacy, EP, Phillips, IR

Superior Title: EUROPEAN JOURNAL OF HUMAN GENETICS , 23 (9) (2015)

Subject Terms: Science & Technology, Life Sciences & Biomedicine, Biochemistry & Molecular Biology, Genetics & Heredity, FISH-ODOR SYNDROME, MONOOXYGENASE 3 GENE, FLAVIN-CONTAINING-MONOOXYGENASE-3 FMO3 GENE, TRANSIENT TRIMETHYLAMINURIA, JAPANESE POPULATION, FUNCTIONAL-ANALYSIS, N-OXIDATION, FLAVIN, MUTATIONS, VARIANTS

Availability: http://discovery.ucl.ac.uk/1452678/

Authors: Hernandez, D, Janmohamed, A, Chandan, P, Omar, BA, Phillips, IR, Shephard, EA

Superior Title: PHARMACOGENET GENOM , 19 (4) 289 - 299. (2009)

Subject Terms: behavioural response, chromosomal engineering, drug metabolism, flavin-containing monooxygenase, imipramine, knockout mice, pharmacogenetics, FLAVIN-CONTAINING MONOOXYGENASES, PERFORMANCE LIQUID-CHROMATOGRAPHY, N-OXIDE, HUMAN LIVER, METABOLISM, EXPRESSION, PLASMA, DESIPRAMINE, MICE, POLYMORPHISM

Availability: http://discovery.ucl.ac.uk/182826/

Authors: Melgarejo-Torres, R, Castillo-Araiza, O, Lopez-Ordaz, P, Torres-Martinez, D, Gutierrez-Rojas, M, Lye, GJ, Huerta-Ochoa, S

Superior Title: CHEMICAL ENGINEERING JOURNAL , 240 1 - 9. (2014)

Subject Terms: Bioconversion, Cyclohexanone monooxygenase, Modelling, Kinetic parameters, Oxygen inactivation, Escherichia coli

Availability: http://discovery.ucl.ac.uk/1427869/

Authors: Shephard, EA, Chandan, P, Stevanovic-Walker, M, Edwards, M, Phillips, IR

Superior Title: BIOCHEM J , 406 491 - 499. (2007)

Subject Terms: alternative promoter, flavin-containing monooxygenase 1 (FMO1), gene regulation, long-interspersed nuclear element (LINE), promoter, retrotransposon, FLAVIN-CONTAINING MONOOXYGENASES, FULL-LENGTH HUMAN, PRIMARY SEQUENCE, FMO1, CLONING, LIVER, IDENTIFICATION, PROGRAM, RABBIT, FAMILY

Availability: http://discovery.ucl.ac.uk/153390/

Authors: Hernandez, D, I R, S, E, A

Contributors: Phillips, IR, Shephard, EA

Superior Title: In: Phillips, IR and Shephard, EA, (eds.) Cytochrome P450 protocols. (pp. 321-327). Humana Press: Totowa, New Jersey. (2006)

Subject Terms: flavin-containing monooxygenase genes, Fmo1, Fmo2, Fmo4, karyotyping, embryonic stem cells, gene deletion, chromosome 1

Availability: http://discovery.ucl.ac.uk/99416/

Authors: Lye, GJ

Superior Title: Presented at: European Federation of Biotechnology meeting. (2003)

Subject Terms: Baeyer-Villiger, biocatalysis, biochemical, biotechnology, engineering, european, microscale processing, Monooxygenase

Availability: http://discovery.ucl.ac.uk/109409/

Authors: Lye, GJ

Superior Title: Presented at: Biochemical Engineering XII. (2003)

Subject Terms: Baeyer-Villiger, biocatalysis, biochemical, engineering, July, microscale processing, Monooxygenase

Availability: http://discovery.ucl.ac.uk/109408/

Authors: Phillips, IR, Shephard, EA

Contributors: Creighton, TE

Superior Title: In: Creighton, TE, (ed.) Wiley Encylopedia of Molecular Medicine. (pp. 1297-1299). John Wiley and Sons: New York. (2002)

Subject Terms: flavin, medicine, Molecular, monooxygenases

Availability: http://discovery.ucl.ac.uk/99429/

Authors: Shephard, EA, Phillips, IR

Contributors: Creighton, TE

Superior Title: In: Creighton, TE, (ed.) Wiley Encyclopedia of Molecular Medicine. (pp. 2132-2136). John Wiley and Sons: New York. (2002)

Subject Terms: medicine, Molecular, monooxygenases

Availability: http://discovery.ucl.ac.uk/99430/

Authors: Krueger, SK, Williams, DE, Yeuch, MF, Martin, SR, Hines, RN, Dolphin, CT, Shephard, EA

Superior Title: Presented at: Genetic polymorphisms of flavin-containg monooxygenase (FMO). (2001)

Subject Terms: monooxygenase

Availability: http://discovery.ucl.ac.uk/99428/

Authors: Zhou, YP, Adolfs, Y, Pijnappel, WWMP, Fuller, SJ, Van der Schors, RC, Li, KW, Sugden, PH, Smit, AB, Hergovich, A, Pasterkamp, RJ

Superior Title: MOL CELL BIOL , 31 (17) 3603 - 3615. (2011)

Subject Terms: ORGAN SIZE CONTROL, PROTEIN-KINASE, FLAVOPROTEIN MONOOXYGENASES, FAD-BINDING, PHOSPHORYLATION, GUIDANCE, PATHWAY, FAMILY, SEMAPHORINS, ACTIVATION

Availability: http://discovery.ucl.ac.uk/1317322/

Authors: Allerston, CK, Vetti, HH, Houge, G, Phillips, IR, Shephard, EA

Superior Title: MOL GENET METAB , 98 (1-2) 198 - 202. (2009)

Subject Terms: Fish-odour syndrome, Flavin-containing monooxygenase, FMO3, Mutation, Norway, Trimethylaminuria, FISH-ODOR SYNDROME, TRANSIENT TRIMETHYLAMINURIA, FUNCTIONAL-ANALYSIS, POLYMORPHISMS, VARIANTS, IDENTIFICATION, METABOLISM, EXPRESSION, POPULATION, MOUSE

Availability: http://discovery.ucl.ac.uk/177670/

Authors: Hilker, I, Gutierrez, MC, Furstoss, R, Ward, J, Wohlgemuth, R, Alphand, V

Superior Title: NAT PROTOC , 3 (3) 546 - 554. (2008)

Subject Terms: CHEMOENZYMATIC SYNTHESIS, OXIDATION PROCESS, BIOCATALYSIS, TRANSFORMATIONS, REDUCTION, MONOOXYGENASES, OXYGEN

Availability: http://discovery.ucl.ac.uk/46148/

Authors: Nichols, LA, Chen, Y, Colella, TA, Bennett, CL, Clausen, BE, Engelhard, VH

Superior Title: J Immunol , 179 (2) 993 - 1003. (2007)

Subject Terms: Adoptive Transfer, Animals, Antigens, Neoplasm, Autoantigens, CD8-Positive T-Lymphocytes, Immunohistochemistry, Lymph Nodes, Melanocytes, Melanoma, Mesentery, Mice, Transgenic, Monophenol Monooxygenase, Radiation Chimera, Radiation Tolerance, Receptors, Antigen, T-Cell, Reverse Transcriptase Polymerase Chain Reaction, Self Tolerance, T-Lymphocyte Subsets

Availability: http://discovery.ucl.ac.uk/1366525/

Authors: Allerston, CK, Shimizu, M, Fujieda, M, Shephard, EA, Yamazaki, H, Phillips, IR

Superior Title: PHARMACOGENET GENOM , 17 (10) 827 - 839. (2007)

Subject Terms: balancing selection, evolution, flavin-containing monooxygenase, FMO, haplotype, human, linkage disequilibrium, mutation, nucleotide diversity, single-nucleotide polymorphism, SINGLE NUCLEOTIDE POLYMORPHISMS, FISH-ODOR SYNDROME, NATURAL-SELECTION, STATISTICAL TESTS, FUNCTIONAL-ANALYSIS, SEQUENCE VARIATION, POPULATION-GROWTH, DNA POLYMORPHISM, HUMAN GENOME, HUMAN LIVER

Availability: http://discovery.ucl.ac.uk/182821/

Authors: Law, HEM, Baldwin, CVF, Chen, BH, Woodley, JM

Superior Title: CHEMICAL ENGINEERING SCIENCE , 61 (20) pp. 6646-6652. (2006)

Subject Terms: biocatalysis, optimisation, mathematical modelling, enzyme, oxidation, Baeyer-Villiger monooxygenase

Availability: http://discovery.ucl.ac.uk/58890/