Authors: 吳建陞, Wu, Chien-Sheng

Contributors: 余家利, 臺灣大學：臨床醫學研究所

Subject Terms: 全身性紅斑狼瘡, 多形核嗜中性白血球, 葡萄糖傳送, 乳酸濃度, 葡萄糖螢光類同物, 葡萄糖傳送分子, SLE, PMN, glucose fluorescence analogue, lactate concentration, glucose transporter, glucose transport

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J Immunol 1993; 150:5124-34. 47. Yamamori T, Inanami O, Nagahata H, Kuwabara M. Phosphoinositide 3-kinase regulates the phosphorylation of NADPH oxidase component p47(phox) by controlling cPKC/PKC delta but not Akt. Biochem Biophys Res Commun 2004; 316:720-30. 48. Yu CL, Chang KL, Chiu CC, Chiang BN, Han SH, Wang SR. Defective phagocytosis, decreased tumor necrosis factor-α production, and lymphocyte hypo-responsiveness predispose patients with systemic lupus erythematosus to infection. Scand J Rheumatol 1989; 18:97-105. 49. Zurier RB. Reduction of phagocytosis and lysosomal enzyme release from human leukocytes by serum from patients with systemic llupus erythematosus. Arthritis Rheum 1976; 19:73-8.; zh-TW; http://ntur.lib.ntu.edu.tw/handle/246246/55565; http://ntur.lib.ntu.edu.tw/bitstream/246246/55565/1/ntu-93-P91421030-1.pdf

Availability: http://ntur.lib.ntu.edu.tw/handle/246246/55565
http://ntur.lib.ntu.edu.tw/bitstream/246246/55565/1/ntu-93-P91421030-1.pdf

Authors: CHIEN, KUO-LIONG, LEE, YUAN-TEH, SUNG, FUNG-CHANG, HSU, HSIU-CHING, SU, TA-CHEN, LIN, RUE-SHEN, 簡國龍, 李源德, 宋鴻樟, 許秀卿, 蘇大成, 林瑞雄

Contributors: 預防醫學研究所, Institute of Preventive Medicine

Subject Terms: CORONARY HEART-DISEASE, INSULIN-RESISTANCE, GLUCOSE- INTOLERANCE, FASTING INSULIN, BLOOD-PRESSURE, PLASMA-GLUCOSE

Relation: CLINICAL CHEMISTRY v.45 n.6 (PT.1) pp.838-846; http://ntur.lib.ntu.edu.tw/handle/246246/81615; http://ntur.lib.ntu.edu.tw/bitstream/246246/81615/1/11.pdf

Availability: http://ntur.lib.ntu.edu.tw/handle/246246/81615
http://ntur.lib.ntu.edu.tw/bitstream/246246/81615/1/11.pdf

Authors: 何弘棋, 陳明豐, 黃瑞仁, 李源德, 蘇大成, HO, HUNG-CHI, CHEN, MING-FONG, HWANG, JUEY-JEN, LEE, YUAN-TEH, SU, TA-CHEN

Contributors: 內科

Subject Terms: Site-specific atherosclerosis, Linear mixed model, Oral glucose tolerance test, Intima-media thickness

Relation: JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS v.16 n.6 pp.748-755; http://ntur.lib.ntu.edu.tw/handle/246246/185828

Availability: http://ntur.lib.ntu.edu.tw/handle/246246/185828

Authors: 萬國良, Wann, Joseph G.

Contributors: 陳朝峰, 臺灣大學：生理學研究所

Subject Terms: 血液透析, 紅血球, 抗壞血酸, 第一型葡萄糖轉運蛋白, 嗜中性白血球, 代謝性酸中毒, 細胞凋亡, haemodialysis, erythrocyte, ascorbate, glucose transporter 1, neutrophil, metabolic acidosis, apoptosis

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Availability: http://ntur.lib.ntu.edu.tw/handle/246246/63559

Authors: 王蓉萱, Wang, Jung-Hsuan

Contributors: 孫岩章, 臺灣大學：植物病理與微生物學研究所

Subject Terms: 有機污染物, 植物毒害, 葡萄糖-麩胺酸溶液, 沙拉油, 礦物油, 酚, organic pollutants, phytotoxicity, glucose-glutamic acid solution, soybean oil, mineral oil, phenol

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Some effects of sodium chloride on growth, photosynthesis and respiration of twelve crop plants. Bot. Gaz. 123:279-285. Petukhov VN, Fomchenkov VM, Chugunov VA, Kholodenko VP. 2000. Plant biotests for soil and water contaminated with oil and oil products. Applied Biochemistry and Microbiology 36(6):564-567. Reynolds T. 1987. Comparative effects of alicyclic compounds and quinones on inhibition of lettuce fruit germination. Annals of Botany 41:637-648. Russell DA, Wong DML, Sachs MM. 1990. The anaerobic response of soybean. Plant Physiology 92(2):401-407. Tagawa T, Ishizaka N. 1963. Physiological studies on the tolerance of rice plants to salinity II-Effects of salinity on the absorption of water and chloride ion. Proc. Crop. Sci. Soc. Jap. 31:337-341. Tan BL, Sarafis V, Beattie GAC, White R, Darley EM, Spooner-Hart R. 2005. Localization and movement of mineral oil in plants by fluorescence and confocal microscopy. Journal of Experimental Botany 56(420):2755-2763. 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Rice seed toxicity tests for organic and inorganic substances. Environmental Monitoring and Assessment 29(2):101-107. Wang XD, Sun C, Gao SX, Wang LS, Han SK. 2001. Validation of germination rate and root elongation as indicator to assess phytotoxicity with Cucumis sativus. Chemosphere 44(8):1711-1721. Wu FY, Sun EJ. 1998. Effects of copper, zinc, nickel, chromium and lead on the growth of water convolvulus in water culture. Environmental Protection 21:63-72. Yoon CG, Kwun SK, Ham JH. 2001. Effects of treated sewage irrigation on paddy rice culture and its soil. Irrigation and Drainage 50(3):227-236.; zh-TW; http://ntur.lib.ntu.edu.tw/handle/246246/58043; http://ntur.lib.ntu.edu.tw/bitstream/246246/58043/1/ntu-96-R94633004-1.pdf

Availability: http://ntur.lib.ntu.edu.tw/handle/246246/58043
http://ntur.lib.ntu.edu.tw/bitstream/246246/58043/1/ntu-96-R94633004-1.pdf

Authors: 吳菁山, Wu, Jing-Shan

Contributors: 林君榮, 臺灣大學：藥學研究所

Subject Terms: 胎盤, 葡萄糖轉運蛋白, 子宮內胎兒生長遲緩, placenta, glucose transporter, GLUT1, GLUT3, intrauterine growth retadation(IUGR), phenobarbital

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Availability: http://ntur.lib.ntu.edu.tw/handle/246246/55645
http://ntur.lib.ntu.edu.tw/bitstream/246246/55645/1/ntu-96-R94423016-1.pdf

Authors: 張齡尹, Chang, Ling-Yin

Contributors: 莊立民, 臺灣大學：臨床醫學研究所

Subject Terms: 肥胖, 葡萄糖代謝, 脂肪代謝, LPIN1基因, obesity, glucose, lipid, LPIN1 gene

File Description: 491274 bytes; application/pdf

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Endocr.Rev. 21:697-738, 2000 Wei JN, Sung FC, Lin CC, Lin RS, Chiang CC, Chuang LM: National surveillance for type 2 diabetes mellitus in Taiwanese children. JAMA 290:1345-1350, 2003 Wild S, Roglic G, Green A, Sicree R, King H (2004) Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 27:1047–1053 Yang WS, Lee WJ, Funahashi T, Tanaka S, Matsuzawa Y, Chao CL, Chen CL, Tai TY, Chuang LM: Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin. J.Clin.Endocrinol.Metab 86:3815-3819, 2001 Yao-Borengasser, A., Rasouli, N., Varma, V. et al. Lipin expression is attenuated in adipose tissue of insulin-resistant human subjects and increases with peroxisome proliferator-activated receptor gamma activation. Diabetes. 2006 Oct;55(10):2811-8.; zh-TW; http://ntur.lib.ntu.edu.tw/handle/246246/55457; http://ntur.lib.ntu.edu.tw/bitstream/246246/55457/1/ntu-96-P93421019-1.pdf

Availability: http://ntur.lib.ntu.edu.tw/handle/246246/55457
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Authors: 郭桂伶, Kuo, Kuei-Ling

Contributors: 林榮信, 臺灣大學：藥學研究所

Subject Terms: 分子動力學, 嵌合模擬, 葡萄糖運輸途徑, GLUT1, glucose transport pathway, MD, dynamics, AMBER, AutoDock

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Glucose transporter type 1 deficiency syndrome (Glut1DS): Methylxanthines potentiate GLUT1 haploinsufficiency in vitro. Pediatric Research 50, 254-260 (2001). 30. Vera, J.C. et al. Direct inhibition of the hexose transporter GLUT1 by tyrosine kinase inhibitors. Biochemistry 40, 777-790 (2001). 31. Vera, J.C. et al. Genistein is a natural inhibitor of hexose and dehydroascorbic acid transport through the glucose transporter, GLUT1. Journal of Biological Chemistry 271, 8719-8724 (1996). 32. Wellner, M., Mueckler, M.M. & Keller, K. Gtp Analogs Suppress Uptake but Not Transport of D-Glucose Analogs in Glut1 Glucose Transporter-Expressing Xenopus-Oocytes. Febs Letters 327, 95-98 (1993). 33. Matsumura, F. Mechanism of Action of Dioxin-Type Chemicals, Pesticides, and Other Xenobiotics Affecting Nutritional Indexes. American Journal of Clinical Nutrition 61, S695-S701 (1995). 34. Pinkofsky, H.B., Dwyer, D.S. & Bradley, R.J. The inhibition of GLUT1 glucose transport and cytochalasin B binding activity by tricyclic antidepressants. Life Sciences 66, 271-278 (2000). 35. Stephenson, K.N., Croxen, R.L., El-Barbary, A., Fenstermacher, J.D. & Haspel, H.C. Inhibition of glucose transport and direct interactions with type 1 facilitative glucose transporter (GLUT-1) by etomidate, ketamine, and propofol - A comparison with barbiturates. Biochemical Pharmacology 60, 651-659 (2000). 36. Klepper, J., Fischbarg, J., Vera, J.C., Wang, D. & De Vivo, D.C. GLUT1-deficiency: Barbiturates potentiate haploinsufficiency in vitro. Pediatric Research 46, 677-683 (1999). 37. Wang, D. et al. Glut-1 deficiency syndrome: Clinical, genetic, and therapeutic aspects. Annals of Neurology 57, 111-118 (2005). 38. Klepper, J. et al. Defective glucose transport across brain tissue barriers: A newly recognized neurological syndrome. Neurochemical Research 24, 587-594 (1999). 39. Wang, D., Kranz-Eble, P. & De Vivo, D.C. 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Availability: http://ntur.lib.ntu.edu.tw/handle/246246/55643
http://ntur.lib.ntu.edu.tw/bitstream/246246/55643/1/ntu-95-R93423009-1.pdf

Authors: 戴仰霞, Dai, Yang-Shia

Contributors: 余幸司, 臺灣大學：臨床醫學研究所

Subject Terms: 嬰兒型血管瘤, 第一型葡萄糖運輸蛋白, 鹼性纖維母細胞生長因子, 血管內皮細胞生長因子, 免疫組織化學染色法, 蛋白質基因產物9.5, 酪胺酸羥化酶, 活化凋亡蛋白3, 交感神經, hemangioma of infancy, glucose transporter I, basic fibroblast growth factor, vascular endothelial growth factor, immunohistochemistry, protein gene product 9.5, tyrosine hydroxylase, activated caspase 3, sympathetic nerve

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AM J Pediatr Hematol Oncol. 1994; 16:325-8. Vikkula M, Boon LM, Carraway KL, Calvert JT, Diamonti AJ, Goumnerov B, et al. Vascular dysmorphogenesis caused by an activating mutation in the receptor tyrosine kinase TIE2. Cell. 1996; 87:1181-90. Walter JW, North PE, Waner M, Mizeracki A, Blei F, Walker JW, et al. Somatic mutation of vascular endothelial growth factor receptors in juvenile hemangioma. Genes Chromosomes Cancer. 2002; 33:295-303. Waner M, North PE, Scherer KA, Frieden IJ, Waner A, Mihm MC . The nonrandom distribution of facial hemangiomas. Arch Dermatol. 2003; 139:869-75. Welsh O, Olazaran Z, Gomez M, Salas J, Berman B. Treatment of infantile hemangiomas with short-term application of imiquimod 5% cream. J Am Acad Dermatol. 2004; 51:639-42. Yu Y, Varughese J, Brown LF, Mulliken JB, Bischoff J. Increased Tie2 expression, enhanced response to angiopoietin-1, and dysregulated angiopoietin-2 expression in hemangioma-derived endothelial cells. Am J Pathol. 2001; 159:2271-80. Yu Y, Flint AF, Mulliken JB, Wu JK, Bischoff J. Endothelial progenitor cells in infantile hemangioma. Blood. 2004; 103:1373-5. Yu Y, Wylie-Sears J, Boscolo E, Mulliken JB, Bischoff J. Genomic Imprinting of IGF2 is maintained in Infantile Hemangioma despite its High Level of Expression. Mol Med. 2005 1; [Epub ahead of print] Zvulunov A, Metzker A. Hemangiomas and vascular malformations: Unapproved treatments. Clin Dermatol. 2002; 20:660-7.; zh-TW; http://ntur.lib.ntu.edu.tw/handle/246246/55572; http://ntur.lib.ntu.edu.tw/bitstream/246246/55572/1/ntu-95-P92421012-1.pdf

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Authors: 洪崇尹, Hung, Chung-Ying

Contributors: 陳永銘, 臺灣大學：臨床醫學研究所

Subject Terms: 高濃度葡萄糖, 腎間質纖維母細胞, 第一型單核球趨化蛋白質, 訊息傳遞, High glucose, Renal interstitial fibroblasts, Monocyte chemoattractant protein-1, Signal transduction

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Studies using tissue culture and electron microscopy. Am J Pathol 1979;94(2):223-240. Van Goor H, Ding G, Kees-Folts D, Grond J, Schreiner GF, Diamond JR. Macrophages and renal disease. Lab Invest 1994;71(4):456-464. Vanden Berghe W, Plaisance S, Boone E, De Bosscher K, Schmitz ML, Fiers W, et al. p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kappaB p65 transactivation mediated by tumor necrosis factor. J Biol Chem 1998;273(6):3285-3290. Viedt C, Dechend R, Fei J, Hansch GM, Kreuzer J, Orth SR. MCP-1 induces inflammatory activation of human tubular epithelial cells: involvement of the transcription factors, nuclear factor-kappaB and activating protein-1. J Am Soc Nephrol 2002;13(6):1534-1547. Wada T, Furuichi K, Sakai N, Iwata Y, Yoshimoto K, Shimizu M, et al. Up-regulation of monocyte chemoattractant protein-1 in tubulointerstitial lesions of human diabetic nephropathy. Kidney Int 2000;58(4):1492-1499. 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Young BA, Johnson RJ, Alpers CE, Eng E, Gordon K, Floege J, et al. Cellular events in the evolution of experimental diabetic nephropathy. Kidney Int 1995;47(3):935-944.; zh-TW; http://ntur.lib.ntu.edu.tw/handle/246246/55540; http://ntur.lib.ntu.edu.tw/bitstream/246246/55540/1/ntu-95-P92421027-1.pdf

Availability: http://ntur.lib.ntu.edu.tw/handle/246246/55540
http://ntur.lib.ntu.edu.tw/bitstream/246246/55540/1/ntu-95-P92421027-1.pdf

Authors: 陳佳壕, Chen, Chia-Hao

Contributors: 林君榮, 臺灣大學：藥學研究所

Subject Terms: 類黃酮素, 小腸的葡萄糖轉運蛋白, 刷狀外緣細胞膜微粒, 微血管側細胞膜微粒, flavonoids, intestinal glucose transporter, BBMV, BLMV

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Pharmacol. 72:317-326 (1994). Turk E, Kerner CJ, Lostao MP, and Wright EM. Membrane topology of the human Na+/glucose cotransporter SGLT1. J. Biol. Chem. 271:1925-1934 (2002). Turner JR. Show me the pathway! Regulation of paracellular permeability by Na+-glucose cotransport. Adv. Drug Deliv. Rev. 41:265-281 (2000). Uldry M, Ibberson M, Hosokawa M, and Thorens B. GLUT2 is a high affinity glucosamine transporter. FEBS Lett. 524:199-203, 2002. Vaidyanathan JB, and Walle T. Cellular uptake and efflux of the tea flavonoid (-)epicatechin-3-gallate in the human intestinal cell line Caco-2. J. Pharmacol. Exp. Ther. 307:745-752 (2003). Vedavanam K, Srijayanta S, O’Reilly J, Raman A, and Wiseman H. Antioxidant action and potential antidiabetic properties of an isoflavonoid -containing soyabean phytochemical extract (SPE). Phytother. Res. 13:601–608 (1999). Walgren RA, Lin JT, Kinne RKH, and Walle T. Cellular uptake of dietary flavonoid quercetin 4'-β-glucoside by sodium-dependent glucose transporter SGLT1. J. Pharmacol. Exp. Ther. 294:837–843 (2000b). Walmsley AR, Barrett MP, Bringaud F, and Gould GW. Sugar transporters frombacteria, parasites and mammals: structure-activity relationships. Trends in Biochem. Sci. 23:476-481 (1998). Wolffram S, Block M, and Ader P. Quercetin-3-glucoside is transported by the glucose carrier SGLT1 across the brush border membrane of rat small intestine. J. Nutr. 132:630–635 (2002). Wright EM, Loo DDF, Mariana PH, Hirayama BA, Turk E, Eskandari S, and Lam JT. Structure and function of the Na+/glucose cotransporter. Acta. Physiol. Scand., 163, suppl. 643:257-264 (1998). Wright EM, Martin MG, and Turk E. Intestinal absorption in health and disease--sugars. Best Pract. Res. Clin. Gastroenterol. 17:943-956 (2003). Wright EM, Van os CH, and Mircheff AK. Sugar uptake by intestinal basolateral membrane vesicles. Biochim. Biophys. Acta 597:112-124 (1980). Yoshino K, Suzuki M, Sasaki K, Miyase T, and Sano M. Formation of antioxidants from (-)-epigallocatechin gallate in mild alkaline fluids, such as authentic intestinal juice and mouse plasma. J. Nutr. Biochem. 10:223-229 (1999). Zhou S, Gao Y, Jiang W, Huang M, Xu A, and Paxton JW. Interactions of herbs with cytochrome P450. Drug Metab. Rev. 35:35-98,2003. Zhu QY, Zhang A, Tsang D, Huang Y, and Chen ZY. Stability of green tea catechins. J. Agric. Food Chem. 45:4624-4628 (1997).; zh-TW; http://ntur.lib.ntu.edu.tw/handle/246246/55621; http://ntur.lib.ntu.edu.tw/bitstream/246246/55621/1/ntu-94-R92423009-1.pdf

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http://ntur.lib.ntu.edu.tw/bitstream/246246/55621/1/ntu-94-R92423009-1.pdf

Authors: 王顏和

Contributors: 國立臺灣大學醫學院復健科

Subject Terms: 脊髓損傷, 頸動脈內中皮層厚度, 口服葡萄糖耐受性測試, Spinal cord injury, carotid intima-media-thickness, oral glucose tolerance test

Subject Geographic: 計畫年度：93, 起迄日期：2004-08-01/2005-07-31

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Relation: 932314B002119; http://ntur.lib.ntu.edu.tw/handle/246246/28987; http://ntur.lib.ntu.edu.tw/bitstream/246246/28987/1/932314B002119.pdf

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http://ntur.lib.ntu.edu.tw/bitstream/246246/28987/1/932314B002119.pdf

Authors: 曾慶孝, TSENG, CHIN-HSIAO

Contributors: 內科

Subject Terms: inorganic arsenic, diabetes mellitus, glucose metabolism, reactive oxygen species, individual susceptibility, environmental pollutants

Relation: TOXICOLOGY AND APPLIED PHARMACOLOGY v.197 n.2 pp.67-83; http://ntur.lib.ntu.edu.tw/handle/246246/95281

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Authors: 林季瑩, Lin, Chi-Ying

Contributors: 鄧述諄, 臺灣大學：微生物學研究所

Subject Terms: 細胞週期, 酵母菌, 葡萄糖, Cell Cycle, Yeast, Glucose, CLN3, YPL014W

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Proc Natl Acad Sci U S A 86: 6255-9. Hall, D.D., D.D. Markwardt, F. Parviz, and W. Heideman. 1998. Regulation of the Cln3-Cdc28 kinase by cAMP in Saccharomyces cerevisiae. Embo J 17: 4370-8. Jeoung, D.I., L.J. Oehlen, and F.R. Cross. 1998. Cln3-associated kinase activity in Saccharomyces cerevisiae is regulated by the mating factor pathway. Mol Cell Biol 18: 433-41. Koch, C., T. Moll, M. Neuberg, H. Ahorn, and K. Nasmyth. 1993. A role for the transcription factors Mbp1 and Swi4 in progression from G1 to S phase. Science 261: 1551-7. Kohrer, K. and H. Domdey. 1991. Preparation of high molecular weight RNA. Methods Enzymol 194: 398-405. Lingner, J. and T.R. Cech. 1998. Telomerase and chromosome end maintenance. Curr Opin Genet Dev 8: 226-32. McKinney, J.D. and F.R. Cross. 1995. FAR1 and the G1 phase specificity of cell cycle arrest by mating factor in Saccharomyces cerevisiae. Mol Cell Biol 15: 2509-16. Mendenhall, M.D. and A.E. Hodge. 1998. Regulation of Cdc28 cyclin-dependent protein kinase activity during the cell cycle of the yeast Saccharomyces cerevisiae. Microbiol Mol Biol Rev 62: 1191-243. Morgan, D.O. 1995. Principles of CDK regulation. Nature 374: 131-4. Nasmyth, K. 1993. Control of the yeast cell cycle by the Cdc28 protein kinase. Curr Opin Cell Biol 5: 166-79. Newcomb, L.L., D.D. Hall, and W. Heideman. 2002. AZF1 is a glucose-dependent positive regulator of CLN3 transcription in Saccharomyces cerevisiae. Mol Cell Biol 22: 1607-14. Parviz, F. and W. Heideman. 1998. Growth-independent regulation of CLN3 mRNA levels by nutrients in Saccharomyces cerevisiae. J Bacteriol 180: 225-30. Polymenis, M. and E.V. Schmidt. 1997. Coupling of cell division to cell growth by translational control of the G1 cyclin CLN3 in yeast. Genes Dev 11: 2522-31. Reed, S.I. 1992. The role of p34 kinases in the G1 to S-phase transition. Annu Rev Cell Biol 8: 529-61. Richardson, H.E., C. Wittenberg, F. Cross, and S.I. Reed. 1989. An essential G1 function for cyclin-like proteins in yeast. Cell 59: 1127-33. Rupes, I. 2002. Checking cell size in yeast. Trends Genet 18: 479-85. Sherlock, G. and J. Rosamond. 1993. Starting to cycle: G1 controls regulating cell division in budding yeast. J Gen Microbiol 139 ( Pt 11): 2531-41. Singer, M.S. and D.E. Gottschling. 1994. TLC1: template RNA component of Saccharomyces cerevisiae telomerase. Science 266: 404-9. Spellman, P.T., G. Sherlock, M.Q. Zhang, V.R. Iyer, K. Anders, M.B. Eisen, P.O. Brown, D. Botstein, and B. Futcher. 1998. Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization. Mol Biol Cell 9: 3273-97. Sudbery, P.E., A.R. Goodey, and B.L. Carter. 1980. Genes which control cell proliferation in the yeast Saccharomyces cerevisiae. Nature 288: 401-4. Teng, S.C., J. Chang, B. McCowan, and V.A. Zakian. 2000. Telomerase-independent lengthening of yeast telomeres occurs by an abrupt Rad50p-dependent, Rif-inhibited recombinational process. Mol Cell 6: 947-52. Teng, S.C., C. Epstein, Y.L. Tsai, H.W. Cheng, H.L. Chen, and J.J. Lin. 2002. Induction of global stress response in Saccharomyces cerevisiae cells lacking telomerase. Biochem Biophys Res Commun 291: 714-21. Teng, S.C. and V.A. Zakian. 1999. Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae. Mol Cell Biol 19: 8083-93. Tyers, M., G. Tokiwa, and B. Futcher. 1993. Comparison of the Saccharomyces cerevisiae G1 cyclins: Cln3 may be an upstream activator of Cln1, Cln2 and other cyclins. Embo J 12: 1955-68. Tyers, M., G. Tokiwa, R. Nash, and B. Futcher. 1992. The Cln3-Cdc28 kinase complex of S. cerevisiae is regulated by proteolysis and phosphorylation. Embo J 11: 1773-84. Uetz, P., L. Giot, G. Cagney, T.A. Mansfield, R.S. Judson, J.R. Knight, D. Lockshon, V. Narayan, M. Srinivasan, P. Pochart, A. Qureshi-Emili, Y. Li, B. Godwin, D. Conover, T. Kalbfleisch, G. Vijayadamodar, M. Yang, M. Johnston, S. Fields, and J.M. Rothberg. 2000. A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature 403: 623-7. Verma, R., R.M. Feldman, and R.J. Deshaies. 1997. SIC1 is ubiquitinated in vitro by a pathway that requires CDC4, CDC34, and cyclin/CDK activities. Mol Biol Cell 8: 1427-37. Wijnen, H., A. Landman, and B. Futcher. 2002. The G(1) cyclin Cln3 promotes cell cycle entry via the transcription factor Swi6. Mol Cell Biol 22: 4402-18. Yaglom, J., M.H. Linskens, S. Sadis, D.M. Rubin, B. Futcher, and D. Finley. 1995. p34Cdc28-mediated control of Cln3 cyclin degradation. Mol Cell Biol 15: 731-41. Yaglom, J.A., A.L. Goldberg, D. Finley, and M.Y. Sherman. 1996. The molecular chaperone Ydj1 is required for the p34CDC28-dependent phosphorylation of the cyclin Cln3 that signals its degradation. Mol Cell Biol 16: 3679-84. Yeager, T.R., A.A. Neumann, A. Englezou, L.I. Huschtscha, J.R. Noble, and R.R. Reddel. 1999. Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body. Cancer Res 59: 4175-9. Zakian, V.A. 1996. Structure, function, and replication of Saccharomyces cerevisiae telomeres. Annu Rev Genet 30: 141-72.; zh-TW; http://ntur.lib.ntu.edu.tw/handle/246246/63405; http://ntur.lib.ntu.edu.tw/bitstream/246246/63405/1/ntu-93-R91445102-1.pdf

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http://ntur.lib.ntu.edu.tw/bitstream/246246/63405/1/ntu-93-R91445102-1.pdf

Authors: 許遵愚, Hsu, Tsun-Yu

Contributors: 曹承礎, 臺灣大學：知識管理組

Subject Terms: 搜尋策略, 核心技術專利, 專利地圖, 市場佔有率, 專利分析, 智財權策略, 生醫產業, 技術關鍵字, 血糖機, 專利資料庫, biomedical industry, market share, patent map, core technology patents, patent database, searching strategy, intellectual property strategy, keywords model, glucose meter technology, patent analysis

Relation: 1.Lawrence G.F. “Global corporate competition : who’s Winning, who’s losing, and the R&D factor as one reason why”, Strategic Management Journal, Vol. 10, p449-474, 1989. 2.Cookson, Clive. ‘International R & D’, Chemical Week. New York, pS15, Jun. 26, 1996. 3.Edward M. S. ‘Leading R&D in the pharmaceutical industry’, Research Technology Management, p35-38; 43, 3; May/Jun 2000. 4.Steven C., Catherine M. ‘Corporate governance and firm strategy in the pharmaceutical industry’ discussion papers, Social Science Research Center Berlin, Sept. 1997. 5.U.S. Congress, Office of Technology Assessment, Innovation and Commercialization of Emerging Technology, OTA-BP-ITC-165, Washington DC, Sept. 1995. 6.U.S. Congress, Office of Technology Assessment, Biotechnology in a Global Economy, OTA-BA-494, Washington DC, Oct. 1991. 7.U.S. Congress, Office of Technology Assessment, Science and Engineering indicators, NSB93-1,appendix table 6-12, p456, Washington DC, Oct. 1993. 8.Su-Ming Hsu, ‘Hsinchu biomedical science park :integration of knowledge-base economy and biotechnology- managing Taiwan’s future’ TABC abstract, 2002. 9.http://www.piug.org/an03abst.html, An international conference for patent information professionals- patent analysis, May 3-9, 2003. 10.徐小波, ‘技術移轉與知識產權’, 國立台灣大學智財權管理 Summary of Speech, 2002. 11.Jeffrey J. E., Baiju R. S., John N. V., ‘Intellectual property :Partnering for profit’ The McKINSEY QARTERLY 2002 special edition: Technology. 12.Annie B. ,Introduction of‘The Management of Intellectual Capital’Long Range Planning, Vol. 30, No.3, pp. 364-365, 1997 13.莊立夫, 江炯聰, ‘企業智慧財產權策略-以宏; zh-TW; http://ntur.lib.ntu.edu.tw/handle/246246/54456

Availability: http://ntur.lib.ntu.edu.tw/handle/246246/54456

Authors: CHEN, CHIEN-JEN, 陳建仁

Contributors: 流行病學研究所, Graduate Institute of Epidemiology

Subject Terms: type 2 diabetes, impaired fasting glucose, incidence, Taiwan

Relation: DIABETES RESEARCH AND CLINICAL PRACTICE v.60 n.3 pp.177-182; http://ntur.lib.ntu.edu.tw/handle/246246/81939

Availability: http://ntur.lib.ntu.edu.tw/handle/246246/81939

Authors: SUNG, FUNG-CHANG, LIN, RUE-SHEN, CHUANG, LEE-MING, 宋鴻樟, 林瑞雄, 莊立民

Contributors: 環境衛生研究所, Institute of Environmental Health

Subject Terms: IMPAIRED GLUCOSE-TOLERANCE, INDIAN CHILDREN, INSULIN- RESISTANCE, FETAL GROWTH, 7-YEAR-OLD CHILDREN, MELLITUS

Relation: DIABETES CARE v.26 n.2 pp.343-348; http://ntur.lib.ntu.edu.tw/handle/246246/81811

Availability: http://ntur.lib.ntu.edu.tw/handle/246246/81811

Authors: 戴東原, 呂金盈, 陳志榮, 賴明陽, 陳培哲, 高嘉宏, 李嘉哲, 李宣書, 莊立民, 鄭永銘, TAI, TONG-YUAN, LU, JIN-YNG, CHEN, CHI- LONG, LAI, MING-YANG, CHEN, PEI-JER, KAO, JIA-HORNG, LEE, CHA-ZE, LEE, HSUAN-SHU, CHUANG, LEE-MING, JENG, YUNG-MING

Contributors: 內科

Subject Terms: CHRONIC ACTIVE HEPATITIS, HOMEOSTASIS MODEL ASSESSMENT, TYPE-1 DIABETES-MELLITUS, CHRONIC VIRAL-HEPATITIS, GLUCOSE-TOLERANCE, LIVER-DISEASE

Relation: JOURNAL OF ENDOCRINOLOGY v.178 n.3 pp.457-465; http://ntur.lib.ntu.edu.tw/handle/246246/95260

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Authors: 曾慶孝, 戴東原, 張春琴, 曾慶平, 賴美淑, 林瑞祥, 邱弘毅, 薛玉梅, 許光宏, 陳建仁, TSENG, CHIN-HSIAO, TAI, TONG-YUAN, CHONG, CHOON-KHIM, TSENG, CHING-PING, LAI, MEI-SHU, LIN, BONIFACE JUISIANG, CHIOU, HUNG-YI, HSUEH, YU-MEI, HSU, KUANG-HUNG, CHEN, CHIEN-JEN

Contributors: 內科

Subject Terms: diabetes, mellitus incidence, ingested arsenic, oral glucose tolerance test, water pollutant, PERIPHERAL VASCULAR-DISEASE

Relation: ENVIRONMENTAL HEALTH PERSPECTIVES v.108 n.9 pp.847-851; http://ntur.lib.ntu.edu.tw/handle/246246/95122

Availability: http://ntur.lib.ntu.edu.tw/handle/246246/95122

Authors: CHEN, CHIEN-JEN, 陳建仁

Contributors: 流行病學所

Subject Terms: type 2 diabetes, impaired fasting glucose, prevalence, Taiwan

Relation: DIABETES RESEARCH AND CLINICAL PRACTICE v.44 n.1 pp.59-69; http://ntur.lib.ntu.edu.tw/handle/246246/83494

Availability: http://ntur.lib.ntu.edu.tw/handle/246246/83494