Authors: Badenhorst, Marcha, de Heus, Phebe, Auer, Angelika, Tegtmeyer, Birthe, Stang, Alexander, Dimmel, Katharina, Tichy, Alexander, Kubacki, Jakub, Bachofen, Claudia, Steinmann, Eike, Cavalleri, Jessika M V
Contributors: TWINCORE, Zentrum für experimentelle und klinische Infektionsforschung GmbH,Feodor-Lynen Str. 7, 30625 Hannover, Germany.
Superior Title: Equine veterinary journal ; United States
Subject Terms: ungulate copiparvovirus 6, horse, liver, luciferase immunoprecipitation system, nested polymerase chain reaction, next-generation sequencing
Relation: Equine Vet J. 2021 Mar 11. doi:10.1111/evj.13444. Epub ahead of print.; http://hdl.handle.net/10033/622958; Equine veterinary journal
Authors: Babbar, Anshu, Kumar, Venkatesan Naveen, Bergmann, René, Barrantes, Israel, Pieper, Dietmar H, Itzek, Andreas, Nitsche-Schmitz, D Patric
Contributors: Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7, 38124 Braunschweig, Germany.
Subject Terms: Deoxyribonucleases, Drug Resistance, Bacterial, Genotype, Germany, Humans, India, Multilocus Sequence Typing, Polymerase Chain Reaction, Streptococcal Infections, Streptococcus anginosus, Streptococcus pyogenes, Superantigens, Virulence Factors
Relation: Members of a new subgroup of Streptococcus anginosus harbor virulence related genes previously observed in Streptococcus pyogenes. 2017, 307 (3):174-181 Int. J. Med. Microbiol.; http://hdl.handle.net/10033/621327; International journal of medical microbiology : IJMM
Authors: Poppe, Michael, Wittig, Sascha, Jurida, Liane, Bartkuhn, Marek, Wilhelm, Jochen, Müller, Helmut, Beuerlein, Knut, Karl, Nadja, Bhuju, Sabin, Ziebuhr, John, Schmitz, M Lienhard, Kracht, Michael
Contributors: Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr.7, 38124 Braunschweig, Germany.
Subject Terms: Cell Line, Chromatin, Chromatin Immunoprecipitation, Coronavirus 229E, Human, Coronavirus Infections, Gene Expression Regulation, Humans, Immunoblotting, Laser Capture Microdissection, Microscopy, Fluorescence, NF-kappa B, Oligonucleotide Array Sequence Analysis, Polymerase Chain Reaction, Transcriptome
Relation: The NF-κB-dependent and -independent transcriptome and chromatin landscapes of human coronavirus 229E-infected cells. 2017, 13 (3):e1006286 PLoS Pathog.; http://hdl.handle.net/10033/621223; PLoS pathogens
Authors: De Jaime-Soguero, Anchel, Aulicino, Francesco, Ertaylan, Gokhan, Griego, Anna, Cerrato, Aniello, Tallam, Aravind, Del Sol, Antonio, Cosma, Maria Pia, Lluis, Frederic
Contributors: TwinCore, Zentrum für experimentelle und klinische Infektionsforschung GmbH, Feodor-Lynen-Str. 7, 30625 Hannover, Germany.
Subject Terms: Animals, Base Sequence, Blotting, Western, Cell Cycle, Cell Proliferation, Cells, Cultured, Cyclin-Dependent Kinase Inhibitor p15, Cyclin-Dependent Kinase Inhibitor p16, Gene Expression Regulation, Gene Knockdown Techniques, HEK293 Cells, Hepatocyte Nuclear Factor 1-alpha, Humans, Mice, Transgenic, Mouse Embryonic Stem Cells, Promoter Regions, Genetic, Reverse Transcriptase Polymerase Chain Reaction, Wnt Signaling Pathway
Relation: Wnt/Tcf1 pathway restricts embryonic stem cell cycle through activation of the Ink4/Arf locus. 2017, 13 (3):e1006682 PLoS Genet.; http://hdl.handle.net/10033/621221; PLoS genetics
Authors: Fischer, Julius C, Bscheider, Michael, Eisenkolb, Gabriel, Lin, Chia-Ching, Wintges, Alexander, Otten, Vera, Lindemans, Caroline A, Heidegger, Simon, Rudelius, Martina, Monette, Sébastien, Porosnicu Rodriguez, Kori A, Calafiore, Marco, Liebermann, Sophie, Liu, Chen, Lienenklaus, Stefan, Weiss, Siegfried, Kalinke, Ulrich, Ruland, Jürgen, Peschel, Christian, Shono, Yusuke, Docampo, Melissa, Velardi, Enrico, Jenq, Robert R, Hanash, Alan M, Dudakov, Jarrod A, Haas, Tobias, van den Brink, Marcel R M, Poeck, Hendrik
Contributors: TWINCORE, Zentrum für experimentelle und klinische Infektionsforschung GmbH, Feodor-Lynen-Str. 7, 30625 Hannover, Germany.
Subject Terms: Adaptor Proteins, Signal Transducing, Animals, DEAD Box Protein 58, Graft vs Host Disease, Hematopoietic Stem Cell Transplantation, Interferon Type I, Intestines, Membrane Proteins, Mice, Inbred C57BL, Knockout, Neutrophil Infiltration, Organoids, Polymerase Chain Reaction, Signal Transduction, Transplantation, Homologous
Relation: RIG-I/MAVS and STING signaling promote gut integrity during irradiation- and immune-mediated tissue injury. 2017, 9 (386) Sci Transl Med; http://hdl.handle.net/10033/621208; Science translational medicine
Authors: Schneefeld, Marie, Busche, Tobias, Geffers, Robert, Kalinowski, Jörn, Bange, Franz-Christoph
Contributors: Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7, 38124 Braunschweig, Germany.
Subject Terms: Amino Acid Sequence, Bacterial Proteins, Electrophoretic Mobility Shift Assay, Gene Expression Regulation, Bacterial, Genes, Lysine, Mycobacterium tuberculosis, Promoter Regions, Genetic, Reverse Transcriptase Polymerase Chain Reaction, Sequence Homology, Amino Acid, Trans-Activators, Transcriptome
Relation: The transcriptional regulator LysG (Rv1985c) of Mycobacterium tuberculosis activates lysE (Rv1986) in a lysine-dependent manner. 2017, 12 (10):e0186505 PLoS ONE; http://hdl.handle.net/10033/621175; PloS one
Authors: Kindler, Eveline, Gil-Cruz, Cristina, Spanier, Julia, Li, Yize, Wilhelm, Jochen, Rabouw, Huib H, Züst, Roland, Hwang, Mihyun, V'kovski, Philip, Stalder, Hanspeter, Marti, Sabrina, Habjan, Matthias, Cervantes-Barragan, Luisa, Elliot, Ruth, Karl, Nadja, Gaughan, Christina, van Kuppeveld, Frank J M, Silverman, Robert H, Keller, Markus, Ludewig, Burkhard, Bergmann, Cornelia C, Ziebuhr, John, Weiss, Susan R, Kalinke, Ulrich, Thiel, Volker
Contributors: TWINCORE, Zentrum für experimentelle und klinische Infectionsforschung GmbH, Feodor-Lynen-Str. 7, 30625 Hannover, Germany.
Subject Terms: Animals, Coronaviridae, Coronavirus Infections, Endonucleases, Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Host-Pathogen Interactions, Humans, Immune Evasion, Immunity, Innate, Mice, Inbred C57BL, Real-Time Polymerase Chain Reaction, Viral Proteins
Relation: Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication. 2017, 13 (2):e1006195 PLoS Pathog.; http://hdl.handle.net/10033/621007; PLoS pathogens
Authors: Andritschke, Daniel, Dilling, Sabrina, Emmenlauer, Mario, Welz, Tobias, Schmich, Fabian, Misselwitz, Benjamin, Rämö, Pauli, Rottner, Klemens, Kerkhoff, Eugen, Wada, Teiji, Penninger, Josef M, Beerenwinkel, Niko, Horvath, Peter, Dehio, Christoph, Hardt, Wolf-Dietrich
Contributors: Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7, 38124 Braunschweig, Germany.
Subject Terms: Animals, Bacterial Proteins, Cell Line, Fluorescent Antibody Technique, Genome-Wide Association Study, HeLa Cells, Host-Pathogen Interactions, Humans, Mice, Microfilament Proteins, Nuclear Proteins, RNA, Small Interfering, Real-Time Polymerase Chain Reaction, Salmonella typhimurium
Relation: A Genome-Wide siRNA Screen Implicates Spire1/2 in SipA-Driven Salmonella Typhimurium Host Cell Invasion. 2016, 11 (9):e0161965 PLoS ONE; http://hdl.handle.net/10033/621273; PloS one
Authors: Waffarn, Elizabeth E, Hastey, Christine J, Dixit, Neha, Soo Choi, Youn, Cherry, Simon, Kalinke, Ulrich, Simon, Scott I, Baumgarth, Nicole
Contributors: Twincore Centre of Experimental and Clinical Infection Research, a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, Hannover 30625, Germany.
Subject Terms: Animals, Antigens, CD11b, B-Lymphocyte Subsets, Cell Adhesion, Cell Migration Assays, Leukocyte, Cell Movement, Flow Cytometry, Immunoglobulin M, Influenza A virus, Interferon Type I, Lymph Nodes, Mediastinum, Mice, Orthomyxoviridae Infections, Real-Time Polymerase Chain Reaction
Relation: Infection-induced type I interferons activate CD11b on B-1 cells for subsequent lymph node accumulation. 2015, 6:8991 Nat Commun; http://hdl.handle.net/10033/615621; Nature communications
Authors: Dağ, Franziska, Dölken, Lars, Holzki, Julia, Drabig, Anja, Weingärtner, Adrien, Schwerk, Johannes, Lienenklaus, Stefan, Conte, Ianina, Geffers, Robert, Davenport, Colin, Rand, Ulfert, Köster, Mario, Weiß, Siegfried, Adler, Barbara, Wirth, Dagmar, Messerle, Martin, Hauser, Hansjörg, Cičin-Šain, Luka
Contributors: Helmholtz Centre for infection research, Inhoffenstr. 7, D-38124 Braunschweig, Germany.
Subject Terms: Animals, Cell Separation, Cytomegalovirus, Cytomegalovirus Infections, Disease Models, Animal, Fluorescent Antibody Technique, Gene Expression Regulation, Viral, Gene Silencing, Genes, Immediate-Early, Genome, High-Throughput Nucleotide Sequencing, Interferon Type I, Mice, Reverse Transcriptase Polymerase Chain Reaction, Virus Latency, Virus Replication
Relation: info:eu-repo/grantAgreement/EC/FP7/260934/; Reversible silencing of cytomegalovirus genomes by type I interferon governs virus latency. 2014, 10 (2):e1003962 PLoS Pathog.; http://hdl.handle.net/10033/344188; PLoS pathogens
Authors: Quentmeier, Hilmar, Eberth, Sonja, Romani, Julia, Weich, Herbert A, Zaborski, Margarete, Drexler, Hans G
Contributors: Helmholtz Centre for infection research, Inhoffenstr. 7, 38124 Braunschweig, Germany.
Subject Terms: Blotting, Western, Cell Line, Tumor, DNA Methylation, Endothelial Cells, Gene Expression Regulation, Human Umbilical Vein Endothelial Cells, Humans, Leukemia, Lymphoma, Real-Time Polymerase Chain Reaction, Sequence Analysis, DNA, Vascular Endothelial Growth Factor Receptor-2, Vascular Endothelial Growth Factor Receptor-3
Relation: DNA methylation regulates expression of VEGF-R2 (KDR) and VEGF-R3 (FLT4). 2012, 12:19 BMC Cancer; http://hdl.handle.net/10033/620842; BMC cancer
Contributors: Helmholtz Centre for infection research, Inhoffenstr. 7, 38124 Braunschweig, Germany.
Subject Terms: Cloning, Molecular, Cluster Analysis, Dioxygenases, Metagenome, Molecular Sequence Data, Phylogeny, Polychlorinated Biphenyls, Polymerase Chain Reaction, Sequence Analysis, DNA, Sequence Homology, Amino Acid, Soil Microbiology, Soil Pollutants
Relation: Characterization of biphenyl dioxygenase sequences and activities encoded by the metagenomes of highly polychlorobiphenyl-contaminated soils. 2012, 78 (8):2706-15 Appl. Environ. Microbiol.; http://hdl.handle.net/10033/620826; Applied and environmental microbiology
Authors: Kashani, Elham, Föhse, Lisa, Raha, Solaiman, Sandrock, Inga, Oberdörfer, Linda, Koenecke, Christian, Suerbaum, Sebastian, Weiss, Siegfried, Prinz, Immo
Contributors: Helmholtz Centre for infection research, Inhoffenstr. 7, 38124 Braunschweig, Germany.
Subject Terms: Amino Acid Motifs, Amino Acid Sequence, Animals, Antigens, CD27, Cell Movement, Germ-Line Mutation, Green Fluorescent Proteins, Immunity, Innate, Mice, Inbred C57BL, Transgenic, Molecular Sequence Data, Phenotype, Polymerase Chain Reaction, Receptors, Antigen, T-Cell, gamma-delta, CCR6, Sequence Analysis, DNA, Single-Cell Analysis, T-Lymphocyte Subsets, Thymus Gland, Tissue Distribution
Relation: A clonotypic Vγ4Jγ1/Vδ5Dδ2Jδ1 innate γδ T-cell population restricted to the CCR6⁺CD27⁻ subset. 2015, 6:6477 Nat Commun; http://hdl.handle.net/10033/611701; Nature communications
Contributors: Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research (HZI), 38124 Braunschweig, Germany.
Subject Terms: Base Sequence, DNA Primers, Electrophoresis, Capillary, Environmental Monitoring, Genotype, Germany, Legionella pneumophila, Molecular Sequence Data, Polymerase Chain Reaction, RNA, Ribosomal, 16S, Reverse Transcriptase Polymerase Chain Reaction, Sequence Analysis, DNA, Tandem Repeat Sequences, Water Microbiology, Water Supply
Relation: High-resolution in situ genotyping of Legionella pneumophila populations in drinking water by multiple-locus variable-number tandem-repeat analysis using environmental DNA. 2010, 76 (18):6186-95 Appl. Environ. Microbiol.; http://hdl.handle.net/10033/123882; Applied and environmental microbiology
Authors: Szafranska, Anna K, Oxley, Andrew P A, Chaves-Moreno, Diego, Horst, Sarah A, Roßlenbroich, Steffen, Peters, Georg, Goldmann, Oliver, Rohde, Manfred, Sinha, Bhanu, Pieper, Dietmar H, Löffler, Bettina, Jauregui, Ruy, Wos-Oxley, Melissa L, Medina, Eva
Contributors: Helmholtz Centre for infection research, Inhoffenstr. 7, 38124 Braunschweig, Germany.
Subject Terms: Adaptation, Physiological, Animals, Disease Models, Animal, Gene Expression, Gene Expression Profiling, Mice, Osteomyelitis, Real-Time Polymerase Chain Reaction, Staphylococcus aureus, Stress
Relation: High-resolution transcriptomic analysis of the adaptive response of Staphylococcus aureus during acute and chronic phases of osteomyelitis. 2014, 5 (6): MBio; http://hdl.handle.net/10033/575929; mBio
Authors: Scherer, Olga, Steinmetz, Heinrich, Kaether, Christoph, Weinigel, Christina, Barz, Dagmar, Kleinert, Hartmut, Menche, Dirk, Müller, Rolf, Pergola, Carlo, Werz, Oliver
Contributors: Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Campus C23, D-66123 Saarbrücken, Germany.
Subject Terms: Base Sequence, Cell Line, Cytokines, DNA Primers, Dose-Response Relationship, Drug, Endoplasmic Reticulum, Humans, Macrolides, Microscopy, Fluorescence, Monocytes, Phosphorylation, Reverse Transcriptase Polymerase Chain Reaction, Signal Transduction, Vacuolar Proton-Translocating ATPases
Relation: Targeting V-ATPase in primary human monocytes by archazolid potently represses the classical secretion of cytokines due to accumulation at the endoplasmic reticulum. 2014, 91 (4):490-500 Biochem. Pharmacol.; http://hdl.handle.net/10033/346155; Biochemical pharmacology
Authors: Song, Lifu, Sudhakar, Padhmanand, Wang, Wei, Conrads, Georg, Brock, Anke, Sun, Jibin, Wagner-Döbler, Irene, Zeng, An-Ping
Contributors: Helmholtz Centre for infection research, Inhoffenstr. 7, D-38124 Braunschweig, Germany.
Subject Terms: Amino Acid Sequence, Bacterial Proteins, Genes, Bacterial, Genomics, Molecular Sequence Data, Polymerase Chain Reaction, Protein Kinases, Protein Structure, Tertiary, Sequence Homology, Amino Acid, Signal Transduction, Species Specificity, Streptococcus mutans
Relation: A genome-wide study of two-component signal transduction systems in eight newly sequenced mutans streptococci strains. 2012, 13:128 BMC Genomics; http://hdl.handle.net/10033/594421; BMC genomics
Authors: Hansen, Wiebke, Hutzler, Marina, Abel, Simone, Alter, Christina, Stockmann, Christian, Kliche, Stefanie, Albert, Juliane, Sparwasser, Tim, Sakaguchi, Shimon, Westendorf, Astrid M, Schadendorf, Dirk, Buer, Jan, Helfrich, Iris
Contributors: Institute of Medical Microbiology, University Hospital Essen, University Duisburg-Essen, 45122 Essen, Germany. wiebke.hansen@uk-essen.de
Subject Terms: Animals, CD4-Positive T-Lymphocytes, CD8-Positive T-Lymphocytes, Cell Line, Tumor, Cell Movement, Flow Cytometry, Forkhead Transcription Factors, Gene Expression Regulation, Neoplastic, Humans, Immunohistochemistry, Lymphocyte Activation, Melanoma, Experimental, Mice, Inbred C57BL, Knockout, Transgenic, Neuropilin-1, Reverse Transcriptase Polymerase Chain Reaction, Skin Neoplasms, T-Lymphocytes, Regulatory, Tumor Burden, Tumor Escape, Vascular Endothelial Growth Factor A
Relation: Neuropilin 1 deficiency on CD4+Foxp3+ regulatory T cells impairs mouse melanoma growth. 2012, 209 (11):2001-16 J. Exp. Med.; http://hdl.handle.net/10033/269936; The Journal of experimental medicine
Contributors: Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Inhoffenstrasse 7, 38124 Braunschweig, Germany.
Subject Terms: Bacteria, Colony Count, Microbial, DNA Fingerprinting, DNA, Bacterial, Drinking Water, Flow Cytometry, Microbial Viability, Molecular Sequence Data, Organic Chemicals, Polymerase Chain Reaction, Polymorphism, Single-Stranded Conformational, Propidium, RNA, Ribosomal, 16S
Relation: Assessing the viability of bacterial species in drinking water by combined cellular and molecular analyses. 2012, 63 (2):383-97 Microb. Ecol.; http://hdl.handle.net/10033/244591; Microbial ecology
Authors: Rohde, Manfred, Graham, Rikki M, Branitzki-Heinemann, Katja, Borchers, Patricia, Preuss, Claudia, Schleicher, Ina, Zähner, Dorothea, Talay, Susanne R, Fulde, Marcus, Dinkla, Katrin, Chhatwal, Gursharan S
Subject Terms: Actins, Adhesins, Bacterial, Bacterial Adhesion, Caveolae, Cell Line, Cytoskeleton, Endocytosis, Fibronectins, Humans, Lysosomes, Microscopy, Electron, Fluorescence, Phagocytosis, Polymerase Chain Reaction, Recombinant Fusion Proteins, Streptococcus, Streptococcus gordonii, Streptococcus pyogenes
Relation: Differences in the aromatic domain of homologous streptococcal fibronectin-binding proteins trigger different cell invasion mechanisms and survival rates. 2011, 13 (3):450-68 Cell. Microbiol.; http://hdl.handle.net/10033/347148; Cellular microbiology